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Low Endotoxin Purified Anti-Human CD11a Antibody [R7-1] (AGEL2085)

SKU:
AGEL2085
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€229 - €1,219
Frequently bought together:

Description

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Product Title:Low Endotoxin Purified Anti-Human CD11a Antibody [R7-1]
SKU:AGEL2085
Size:50µg, 500µg, 1mg
Clone No:R7-1
Synonyms:Integrin alpha-L;LFA-1A;CD11A;ITGAL;
Host Species:Mouse
Reactivity:Human
Application:FCM;FA
Isotype:Mouse IgG1, κ
Isotype Control:AF/LE Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P20701
Gene ID:3683
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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