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Anti-NPY5R Antibody (CAB20207)

SKU:
CAB20207
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
NPYR5
NPY5-R
NPYY5-R
€259 - €359
Frequently bought together:

Description

Product Name:NPY5R Rabbit pAb
Product Code:CAB20207
Size:50uL, 100uL
Synonyms:NPYR5, NPY5-R, NPYY5-R
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NPY5R (NP_001304020.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NPY5R (NP_001304020.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4889
Uniprot:Q15761
Calculated MW:51kDa
Observed MW:Refer to figures
UniProt Protein Function:NPY5R: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 4q31-q32

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:neuropeptide Y receptor activity

Biological Process: cell surface receptor linked signal transduction; feeding behavior; G-protein coupled receptor protein signaling pathway; synaptic transmission

NCBI Summary:The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]
UniProt Code:Q15761
NCBI GenInfo Identifier:215274093
NCBI Gene ID:4889
NCBI Accession:Q15761.2
UniProt Secondary Accession:Q15761,Q6GTR7, Q92916,
UniProt Related Accession:Q15761
Molecular Weight:50,727 Da
NCBI Full Name:Neuropeptide Y receptor type 5
NCBI Synonym Full Names:neuropeptide Y receptor Y5
NCBI Official Symbol:NPY5R  
NCBI Official Synonym Symbols:NPYR5; NPY5-R; NPYY5-R  
NCBI Protein Information:neuropeptide Y receptor type 5
UniProt Protein Name:Neuropeptide Y receptor type 5
UniProt Synonym Protein Names:NPY-Y5 receptor; NPYY5-R; Y5 receptor
Protein Family:Neuropeptide Y receptor
UniProt Gene Name:NPY5R  
UniProt Entry Name:NPY5R_HUMAN

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