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Bcl-2 Polyclonal Antibody (CAB0208)

SKU:
CAB0208
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IHC
IF
IP
€129 - €359
Frequently bought together:

Description

Product Name:Bcl-2 Polyclonal Antibody
Product Code:CAB0208
Reactivity:Human, Mouse
Applications:Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse
Tested Applications:WB, IHC-P, IF/ICC, IP, ELISA
Key Applications:Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation
Recommended Dilution:WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:293T
Cellular Location:Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein
Customer Validation:WB(rat cells, HCT116, B6, MCF-7,MD-MBA-231, Rattus norvegicus, Homo sapiens, Mus musculus, Gallus gallus, Bos taurus, Sus scrofa, Giardia duodenalis, Capra hircus, Ctenopharyngodon, Ctenopharyngodon idellus, lamprey, quails, crab, Apocynum venetum leaf, hsa, Human, Cyprinus Carpio)IHC(Rattus norvegicus, Mus musculus, Homo sapiens, Oreochromis niloticus) IHC(Mus musculus)IF(Homo sapiens, Mus musculus) IHC(Gallus gallus, Mus musculus) IF(Rattus norvegicus) IP(Mus musculus, Rattus norvegicus) ICH(Mus musculus) IF(Mus musculus) RT-PCR(Homo sapiens)IP(Mouse,Rat)

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bcl-2 (NP_000624.2).
Sequence:MAHAG RTGYD NREIV MKYIH YKLSQ RGYEW DAGDV GAAPP GAAPA PGIFS SQPGH TPHPA ASRDP VARTS PLQTP AAPGA AAGPA LSPVP PVVHL TLRQA
Synonyms:Bcl-2, PPP1R50
Calculated MW:26kDa
Observed MW:26kDa

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