Cytokines and growth factors

Recombinant Human NCR3/NKp30 Protein (His Tag)Background:Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering...

Recombinant Human KLRD1/CD94 Protein (His Tag)Background:CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of natural killer cells in the innate immune system...

Recombinant Human APE1/APE Protein (His Tag)Background:The enzyme is known to be a redox factor (Ref) stimulating DNA binding activity of AP binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease,...

Recombinant Human PD-L1/B7-H1/CD274 Protein (Fc & Avi Tag)Background:CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily...

Recombinant Human S100A12/CAGC ProteinBackground:There are at least 21 different S100 proteins and the protein is 100% soluble in ammonium sulfate at neutral pH. S100 proteins play a role in regulation of protein phosphorylation, transcription factors,...

Recombinant Human LIMP-2/LIMPII Protein (His Tag)Background:Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell...

Recombinant Human Calumenin Protein (aa 1-311, His Tag)Background:Calumenin belongs to the CREC family. It contains 6 EF-hand domains. Calumenin is expressed in skeletal muscle (at protein level). Calumenin interacts with GGCX and RYR1 in the presence of...

Recombinant Human STAT3 Protein (His Tag)Background:Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types...

Recombinant Human CD59 Protein (His Tag)Background:CD59 glycoprotein, also known as 20 kDa homologous restriction factor, HRF20, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and...

Recombinant Human Glucagon/GCG Protein (His Tag)Background:Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in...

Recombinant Human APRIL/TNFSF13 Protein (His & Flag Tag)Background:APRIL (a proliferation-inducingligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a32 kDa proprotein which is cleaved...

Recombinant Human Eotaxin-3/CCL26 Protein (aa 27-94)Background:Chemokine (C C Motif) Ligand 26 (CCL26) is a novel small cytokine belonging to the CC chemokine family, which involved in immunoregulatory and inflammatory processes. CCL26 is expressed...

Recombinant Human SMAD3 Protein (His & Flag Tag)Background:Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by...

Recombinant Human SerpinI2 Protein (His Tag)Background:SERPINI2 is a secreted protein of the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. As protease...

Recombinant Human Sonic Hedgehog/SHH Protein (Active)Background:Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key...

Recombinant Human Gankyrin/PSDM10 ProteinBackground:Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation...

Recombinant Human Sonic Hedgehog/SHH Protein (C24II)(Active)Background:Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are...

Recombinant Human SerpinG1/C1IN Protein (His Tag)Background:As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine...

Recombinant Human SerpinF1/PEDF Protein (His Tag)Background:Serpin F1 is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. As...

Recombinant Human SerpinE1/PAI Protein (His Tag)Background:Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. They are the largest and most diverse family of serine protease...

Recombinant Human DMP1 Protein (His Tag)(Active)Background:Dentin matrix acidic phosphoprotein (DMP1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for...

Recombinant Human Cathepsin L/CTSL Protein (His Tag)Background:Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major...

Recombinant Human MAP1LC3A Protein (His Tag)Background:Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) belongs to the MAP1 LC3 family. MAP1LC3A is found most abundantly in the heart, brain, liver, skeletal muscle, and testis. But it is...

Recombinant Human MICA Protein (Fc Tag)(Active)Background:MHC class I polypeptide-related sequence A, also known as MIC-A, PERB11.1 and MICA, is a single-pass type I membrane protein which belongs to the MHC class I family of MIC subfamily. MICA contains...

Recombinant Human Apolipoprotein A-I/ApoAI Protein (aa 19-267, His Tag)Background:Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL)...

Recombinant Human CD3d/CD3 delta Protein (His Tag)Background:CD3D is a single-pass type I membrane protein which Contains 1 ITAM domain. T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular...

Recombinant Human CLPS/Colipase Protein (His Tag)(Active)Background:Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five...

Recombinant Human SHMT1 Protein (His Tag)Background:Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and...

Recombinant Human SENP8 Protein (His Tag)Background:Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from...

Recombinant Human ALDOC Protein (His Tag)Background:Fructose-bisphosphate aldolase C (ALDOC) belongs to the class I fructose-bisphosphate aldolase family. It is an enzyme that, in humans, is encoded by the ALDOC gene. ALDOC is expressed exclusively in...

Recombinant Human MMP1 Protein (His Tag)Background:Matrix Metalloproteinase (MMP) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP1 contains several distinct domains: a prodomain that is cleaved upon...

Recombinant Human ALDOA Protein (His Tag)Background:Fructose Bisphosphate Aldolase A (ALDOA) belongs to the class I fructose-bisphosphate aldolase family. ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose,6-bisphosphate to...

Recombinant Human KEAP1/INRF2 Protein (His & GST & AVI Tag)Background:Kelch-like ECH-associated protein 1, also known as cytosolic inhibitor of Nrf2, Kelch-like protein 19, KEAP1 and INRF2, is a cytoplasm and nucleus protein which contains one BACK...

Recombinant Human E-Cadherin/CDH1 Protein (His Tag)Background:E-Cadherin is a classical member of the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a...

Recombinant Human KEAP1/INRF2 ProteinBackground:Kelch-like ECH-associated protein 1, also known as cytosolic inhibitor of Nrf2, Kelch-like protein 19, KEAP1 and INRF2, is a cytoplasm and nucleus protein which contains one BACK (BTB/Kelch associated)...

Recombinant Human Carbonic Anhydrase 3/CA3 Protein (His Tag)Background:Carbonic Anhydrase 3 (CA3) belongs to the Alpha-Carbonic Anhydrase family that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that...

Recombinant Human Flap Endonuclease 1/FEN1 ProteinBackground:Flap Endonuclease 1 (FEN1) is a member of the XPG/RAD2 endonuclease family. During DNA replication, FEN1 cleaves the 5'-overhanging flap structure and processes the 5' ends of Okazaki fragments...

Recombinant Human Beta-2-Microglobulin/B2M Protein (His Tag)Background:?-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major...

Recombinant Human VDR/NR1I1 Protein (His Tag)Background:VDR (vitamin D(1,25- dihydroxyvitamin D3)receptor), also known as NR1I1, belongs to the NR1I family, NR1 subfamily. It is composed of three domains: a modulating N-terminal domain, a DNA-binding...

Recombinant Human CNPY2 Protein (His Tag)Background:CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin...

Recombinant Human TGFBR2 Protein (Fc Tag)Background:TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered...

Recombinant Human PRPS2 Protein (His Tag)Background:Ribose-Phosphate Pyrophosphokinase 2 (PRPS2) is a phosphoribosyl pyrophosphate synthetase that belongs to the ribose-phosphate pyrophosphokinase family. PRPS2 is a homodimer. The active form is probably...

Recombinant Human Calmodulin/CALM1 ProteinBackground:Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of...

Recombinant Human HRAS/GTPase Hras Protein (His Tag)Background:HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have...

Recombinant Human CRADD/RAIDD ProteinBackground:Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD...

Recombinant Human Catalase/CAT ProteinBackground:Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen...

Recombinant Human TYRO3 Protein (His Tag)Background:Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two...

Recombinant Human LTBR/TNFRSF3 Protein (His Tag)Background:Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis...

Recombinant Human LTBR/TNFRSF3 Protein (Fc Tag)Background:Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor...

Recombinant Human Retinol-Binding Protein 2/RBP2 ProteinBackground:Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. Retinol and retinoic acid play crucial roles in the modulation...

Recombinant Human Eotaxin-3/CCL26 Protein (aa 24-94)Background:Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively...

Recombinant Human FGF0/FGF10 ProteinBackground:Fibroblast growth factor 10 (FGF0, KGF-2), is a member of the fibroblast growth factor (FGF) family that includes FGF-3, -7, and -22. KGF-2 is secreted by mesenchymal cells and associates with extracellular...

Recombinant Human DUSP3/VHR Protein (His Tag)Background:Human DUSP3 belongs to the dual specificity protein phosphatase subfamily. DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and...

Recombinant Human Sonic Hedgehog/SHH Protein (aa 197, His Tag)(Active)Background:Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver,...

Recombinant Human GMPR Protein (E.coli, His Tag)Background:GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family. This family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved in purine metabolism and adopt a TIM...