Cardiovascular

system_update_altDatasheetHuman GLUL Recombinant Protein Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of...

system_update_altDatasheetHuman ALK/ACVRL1 Recombinant Protein Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains,...

system_update_altDatasheetHuman SerpinA10/SERPINA10 Recombinant Protein Serpin A10 is a secreted protein that belongs to the serpin family. It is predominantly expressed in the liver and secreted in the plasma. Its phosphorylation sites are present in...

system_update_altDatasheetHuman ROBO4 Recombinant Protein Roundabout homolog 4; also known as magic roundabout and ROBO4 is a member of the immunoglobulin superfamily and ROBO family. ROBO4 is specifically expressed in endothelial cells. It is...

system_update_altDatasheetCarboxypeptidase B2/CPB2 Recombinant Protein Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen...

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system_update_altDatasheetHuman Thrombomodulin/CD141 Recombinant Protein Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the...

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system_update_altDatasheetHuman VEGFR2/Flk/KDR Recombinant Protein Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental...

system_update_altDatasheetHuman Annexin V/Annexin A5 Recombinant Protein This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex; which is involved in the blood coagulation cascade. annexin A5;...

system_update_altDatasheetCoagulation Factor X/F10 Recombinant Protein F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1-40). Both...

system_update_altDatasheetHuman F13a/Factor XIIIa Recombinant Protein Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The...

system_update_altDatasheetHuman FN14/TWEAKR Recombinant Protein Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It...

system_update_altDatasheetHuman Ephrin-B2/EFNB2 Recombinant Protein Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in...

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system_update_altDatasheetHuman Ephrin-A1/EFNA1 Recombinant Protein Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF...

system_update_altDatasheetHuman FAP/Seprase Recombinant Protein Seprase, also known as 170 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane...

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system_update_altDatasheetHuman EphA1 Recombinant Protein Ephrin type-A receptor 1/EphA1 is a glycosylated member of the Eph family of transmembrane receptor tyrosine kinases. The signaling pathway downstream of the receptor is referred to as forward...

system_update_altDatasheetHuman EphA2 Recombinant Protein Ephrin type-A receptor 2/EphA2 is a member of the Eph receptor tyrosine kinase family which binds Ephrins A1; 2; 3; 4; and 5. A and B class Eph proteins have a common structural organization...

system_update_altDatasheetHuman Endoglin/CD105 Recombinant Protein Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has...

system_update_altDatasheetMFG-E8/lactadherin/MFGE8 Recombinant Protein MFG-E8, also known as lactadherin and MFGE8, contains 1 EGF-like domain and 2 F5/8 type C domains. It also contains a phosphatidylserine (PS) binding domain, as well as an...

system_update_altDatasheetHuman EphB3/HEK2 Recombinant Protein Ephrin type-B receptor 3, also known as EphB3 or HEK2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are...

system_update_altDatasheetHuman EphA2 Recombinant Protein Eph receptor A2 (Ephrin type-A receptor 2 or EphA2) is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptors' corresponding family of ligands are the...

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system_update_altDatasheetHuman ROBO4 Recombinant Protein Roundabout homolog 4(ROBO4) contains 2 fibronectin type-III domains; 2 Ig-like C2-type (immunoglobulin-like) domains and belongs to the immunoglobulin superfamily.The protein is a receptor for...

system_update_altDatasheetHuman ADAM15 Recombinant Protein ADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different...

system_update_altDatasheetHuman MYDGF Recombinant Protein Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen, prostate and lung, and weakly expressed in the left...

system_update_altDatasheetPlasma Kallikrein/KLKB1 Recombinant Protein KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves...

system_update_altDatasheetHuman EphB4/HTK Recombinant Protein Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase...

system_update_altDatasheetHuman Tie1 Recombinant Protein TIE-1 (Tyrosine Kinase with Ig and EGF Homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily. These receptors are expressed on endothelial and hematopoietic...

system_update_altDatasheetHuman FLT1 Recombinant Protein Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor...

system_update_altDatasheetHuman WARS/TrpRS Recombinant Protein There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan...

system_update_altDatasheetHuman EPCR Recombinant Protein Endothelial Protein C Receptor (EPCR) is a Vitamin K-dependent Serine Protease that plays a major role in blood coagulation. Binding of Protein C to EPCR leads to the proteolytic activation of PAR1...

system_update_altDatasheetHuman EphA2 Recombinant Protein Eph receptor A2 (Ephrin type-A receptor 2 or EphA2) is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptors' corresponding family of ligands are the...

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system_update_altDatasheetHumanF13B Recombinant Protein Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein...

system_update_altDatasheetCoagulation Factor VII/F7 Recombinant Protein Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central...

system_update_altDatasheetHuman Tissue Factor/CD142 Recombinant Protein Tissue factor (TF); also known as coagulation factor III; F3; and CD142; is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of...

system_update_altDatasheetHuman tPA/PLAT Recombinant Protein Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and...

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system_update_altDatasheetHuman TFPI2 Recombinant Protein Human Tissue Factor Pathway Inhibitor 2 (TFPI2) has a N-terminal acidic region, three Kunita domains separated with by two linker regions, and a C-terminal basic region. TFPI2 has the function of...

system_update_altDatasheetHuman COL8A1 Recombinant Protein Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement...

system_update_altDatasheetCoagulation Factor IX/F9 Recombinant Protein Coagulation factor IX?F9), is a member of the peptidase S1 family. It contains two EGF-like domains, a Gla domain and a peptidase S1 domain. It is primarily expressed in the liver and...

system_update_altDatasheetHuman Tissue Factor/CD142 Recombinant Protein Tissue Factor (TF) is a single-pass type I membrane glycoprotein member of the tissue factor family. TF expression is highly dependent upon cell type. This factor enables cells to...

system_update_altDatasheetHuman PROC1/Protein C/PROC Recombinant Protein CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of...

system_update_altDatasheetHuman EPCR Recombinant Protein Endothelial protein C receptor (EPCR); also known as activated protein C receptor (APC receptor) or PROCR; is a receptor for Protein C. Protein C plays an important role in many metabolism...

system_update_altDatasheetHuman PROS1/Protein S Recombinant Protein PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood...