CD34 Polyclonal Antibody
- SKU:
- CAB21839
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
CD34 Polyclonal Antibody (CAB21839)
The CD34 Polyclonal Antibody is a valuable tool for researchers studying the CD34 protein, a marker of hematopoietic stem and progenitor cells. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the CD34 protein, this antibody enables detection and analysis in various cell types, making it ideal for studies in stem cell biology and hematopoiesis.CD34 is a transmembrane glycoprotein expressed on the surface of hematopoietic stem cells and endothelial progenitor cells. Its role in hematopoiesis and vascular biology has made it a key target for research in fields such as regenerative medicine, cancer biology, and cardiovascular disease.
Understanding the function and regulation of CD34 is essential for advancing therapeutic approaches in these areas.Overall, the CD34 Polyclonal Antibody offers researchers a reliable tool for studying CD34 expression and function in a variety of experimental settings. Its high specificity and sensitivity make it a valuable asset for furthering our understanding of hematopoietic stem cells and their potential applications in clinical research.
Product Name: | CD34 Polyclonal Antibody |
Product Code: | CAB21839 |
Reactivity: | Human |
Applications: | Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | IF/ICC, ELISA |
Key Applications: | Immunofluorescence |
Recommended Dilution: | IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Membrane, Single-pass type I membrane protein |
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-320 of human CD34 (NP_001020280). |
Sequence: | PYTSS SPILS DIKAE IKCSG IREVK LTQGI CLEQN KTSSC AEFKK DRGEG LARVL CGEEQ ADADA GAQVC SLLLA QSEVR PQCLL LVLAN RTEIS SKLQL MKKHQ SDLKK LGILD FTEQD VASHQ SYSQK TLIAL VTSGA LLAVL GITGY FLMNR RSWSP T |
Synonyms: | CD34, CD34 molecule |
Calculated MW: | 41kDa |
Observed MW: | Refer to figures |