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Low Endotoxin Purified Anti-Human/Monkey CD154/CD40L Antibody [5C8] (AGEL1603)

SKU:
AGEL1603
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
NHP - Monkey
Applications:
FC
$275 - $1,463
Frequently bought together:

Description

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Product Title:Low Endotoxin Purified Anti-Human/Monkey CD154/CD40L Antibody [5C8]
SKU:AGEL1603
Size:50µg, 500µg, 1mg
Clone No:5C8
Synonyms:CD40L; gp39; TRAP; T-BAM; TNFSF5;
Host Species:Mouse
Reactivity:Human;Monkey
Application:FCM;Block
Isotype:Mouse IgG2a, κ
Isotype Control:AF/LE Purified Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P29965
Gene ID:959
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

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