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Anti-FGL1 Antibody (CAB3862)

SKU:
CAB3862
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€129 - €359
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Description

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Antibody Name:Anti-FGL1 Antibody
Antibody SKU:CAB3862
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human FGL1 (NP_004458.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human FGL1 (NP_004458.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAKV FSFI LVTT ALTM GREI SALE DCAQ EQMR LRAQ VRLL ETRV KQQQ VKIK QLLQ ENEV QFLD KGDE NTVI DLGS KRQY ADCS EIFN DGYK LSGF YKIK PLQS PAEF SVYC DMSD GGGW TVIQ RRSD GSEN FNRG WKDY ENGF GNFV QKHG EYWL GNKN LHFL TTQE DYTL KIDL ADFE KNSR YAQY KNFK VGDE KNFY ELNI GEYS GTAG DSLA GNFH PEVQ WWAS HQRM KFST WDRD HDNY EGNC AEED QSGW WFNR CHSA NLNG VYYS GPYT AKTD NGIV WYTW HGWW YSLK SVVM KIRP NDFI PNVI
Gene ID:2267
Uniprot:Q08830
Cellular Location:Secreted
Calculated MW:36kDa
Observed MW:Refer to figures
Synonyms:FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1
Background:Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
UniProt Protein Function:FGL1: Has hepatocyte mitogenic activity.
UniProt Protein Details:

Protein type:Extracellular matrix; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: fibrinogen complex

Biological Process: cholesterol metabolic process

NCBI Summary:Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q08830
NCBI GenInfo Identifier:147744562
NCBI Gene ID:2267
NCBI Accession:Q08830.3
UniProt Secondary Accession:Q08830,Q4PJH9, Q53YF1, Q8NG32, Q96KW6, Q96QM6, A6NKU4
UniProt Related Accession:Q08830
Molecular Weight:312
NCBI Full Name:Fibrinogen-like protein 1
NCBI Synonym Full Names:fibrinogen-like 1
NCBI Official Symbol:FGL1  
NCBI Official Synonym Symbols:HFREP1; HP-041; LFIRE1; LFIRE-1  
NCBI Protein Information:fibrinogen-like protein 1; hepassocin; liver fibrinogen-related protein 1; hepatocellular carcinoma-related sequence; hepatocyte-derived fibrinogen-related protein 1
UniProt Protein Name:Fibrinogen-like protein 1
UniProt Synonym Protein Names:HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1
Protein Family:Fibrinogen-like protein
UniProt Gene Name:FGL1  
UniProt Entry Name:FGL1_HUMAN

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