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Human B7-H2 Recombinant Protein (mFc-His Tag) (HDPT0029)

SKU:
HDPT0029
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint
€683
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Description

Human B7-H2 Recombinant Protein (mFc-His Tag)

Description:Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2.The protein is the ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function
Product name:Human B7-H2 Recombinant Protein (mFc-His Tag)
Synonyms:ICOSLG, B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, LICOS, ICOS ligand
Type:protein
Size:50 µg
Name:B7-H2
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Flow Cyt
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Mouse Fc and 6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:B7H2(Asp19-Thr256)+mFc(Pro99-Lys330)+6×His tag
Gene ID:23308
Uniprot:O75144
Molecular Weight:53.9 kDa