Human ALDOC Recombinant Protein (RPPB1394)
- SKU:
- RPPB1394
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P09972
- Research Area:
- Enzymes
Description
| Product Name: | Human ALDOC Recombinant Protein |
| Product Code: | RPPB1394 |
| Size: | 20µg |
| Species: | Human |
| Target: | ALDOC |
| Synonyms: | Fructose-bisphosphate aldolase C, Brain-type aldolase, ALDOC, ALDC. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear colorless solution. |
| Formulation: | The ALDOC solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYR QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF SYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY |
Aldolase C Fructose-Bisphosphate (ALDOC) belongs to the class I fructose-bisphosphate aldolase family. ALDOC is a glycolytic enzyme which catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively. ALDOC is expressed exclusively in the hippocampus and Purkinje cells of the brain.
ALDOC Human Recombinant fused to a 20 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 384 amino acids (1-364 a.a) and having a molecular mass of 41.6 kDa. The ALDOC is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:EC 4.1.2.13; Lyase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - fructose and mannose Chromosomal Location of Human Ortholog: 17cen-q12 Cellular Component: cytoskeleton; cytosol Molecular Function:cytoskeletal protein binding; fructose-bisphosphate aldolase activity; protein binding Biological Process: epithelial cell differentiation; fructose 1,6-bisphosphate metabolic process; fructose metabolic process; gluconeogenesis |
| NCBI Summary: | This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P09972 |
| NCBI GenInfo Identifier: | 113613 |
| NCBI Gene ID: | 230 |
| NCBI Accession: | P09972.2 |
| UniProt Secondary Accession: | P09972,Q3SYL3, Q6FH94, Q6P0L5, B2R5R3, |
| UniProt Related Accession: | P09972 |
| Molecular Weight: | 39,456 Da |
| NCBI Full Name: | Fructose-bisphosphate aldolase C |
| NCBI Synonym Full Names: | aldolase, fructose-bisphosphate C |
| NCBI Official Symbol: | ALDOC�� |
| NCBI Official Synonym Symbols: | ALDC�� |
| NCBI Protein Information: | fructose-bisphosphate aldolase C |
| UniProt Protein Name: | Fructose-bisphosphate aldolase C |
| UniProt Synonym Protein Names: | Brain-type aldolase |
| Protein Family: | Fructose-bisphosphate aldolase |
| UniProt Gene Name: | ALDOC�� |
| UniProt Entry Name: | ALDOC_HUMAN |
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