Human CD46 Recombinant Protein (His Tag) (HDPT0119)
- SKU:
- HDPT0119
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Frequently bought together:
Description
Human CD46 Recombinant Protein (His Tag)
| Description: | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Product name: | Human CD46 Recombinant Protein (His Tag) |
| Synonyms: | CD46,AHUS2,MCP,MIC10,TLX,TRA2.10 |
| Type: | protein |
| Size: | 50 µg |
| Name: | CD46 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | CD46（Cys35-Asp328）+6×His tag |
| Gene ID: | 4179 |
| Uniprot: | P15529 |
| Molecular Weight: | 55-70 kDa |
