Human Heat Shock 70kDa Protein-8 Recombinant Protein (CPRT5248)

SKU:
CPRT5248
€278

Description

Data SheetMSDS

HSPA8 Human Recombinant Protein

Name:HSPA8 Human
Synonyms:LAP1, HSC54, HSC70, HSC71, HSP1, HSP73, NIP71, HSPA10, MGC29929, MGC131511, HSPA8, Heat shock cognate 71 kDa protein, Heat shock 70 kDa protein 8.
Introduction:HSPA8 is part of the heat shock protein 70 family which includes both heat–inducible and constitutively expressed proteins (heat–shock cognate proteins). HSPA8 is a heat–shock cognate protein that binds to nascent polypeptides to facilitate correct folding. HSPA8 plays a role as an ATPase in the disassembly of clathrin–coated vesicles through transport of membrane components through the cell. HSPA8 is expressed in colon cancer cells, HSPA8 takes part in reovirus outer capsid disassembly, through membrane penetration, to plan the enteringparticle for gene expression and replication. serum HSPA8 concentrations are reduced in normal human pregnancy. HSPA8 plays a role in androgen action on dermal papilla cells. HSPA8 is directly linked with Influenza virus matrix protein 1 and thus required for viral production.
Description:Recombinant Human HSC70 produced in E.Coli is a single, non–glycosylated polypeptide chain containing 666 amino acids (1–646 a.a.) and having a molecular mass of 73.1kDa.HSC70 human recombinant is fused to 20 amino acid His tag at N–terminus and purified by convential chromatogrpahy techniques.
Source:Escherichia Coli.
Pack size:10µg
Physical Appearance:Sterile filtered colorless solution.
Formulation:The HSC70 protein solution contains 20mM Tris, pH–8 & 10% Glycerol.
Solubility:N/A
Stability:Store at 4°C if entire vial will be used within 2–4 weeks. Store, frozen at –20°C for longer periods of time. For longterm storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze–thaw cycles.
Purity:Greater than 90.0% as determined by SDS–PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MSKGPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA MNPTNTVFDA KRLIGRRFDD AVVQSDMKHW PFMVVNDAGR PKVQVEYKGE TKSFYPEEVS SMVLTKMKEI AEAYLGKTVT NAVVTVPAYF NDSQRQATKD AGTIAGLNVL RIINEPTAAA IAYGLDKKVgAERNVLIFDL GGGTFDVSIL TIEDGIFEVK STAGDTHLGgEDFDNRMVNH FIAEFKRKHK KDISENKRAV RRLRTACERA KRTLSSSTQA SIEIDSLYEgIDFYTSITRA RFEELNADLF RGTLDPVEKA LRDAKLDKSQ IHDIVLVGGS TRIPKIQKLL QDFFNGKELN KSINPDEAVA YGAAVQAAIL SGDKSENVQD LLLLDVTPLS LGIETAGGVM TVLIKRNTTI PTKQTQTFTT YSDNQPGVLI QVYEGERAMT KDNNLLGKFE LTGIPPAPRgVPQIEVTFDI DANGILNVSA VDKSTGKENK ITITNDKGRL SKEDIERMVQ EAEKYKAEDE KQRDKVSSKN SLESYAFNMK ATVEDEKLQgKINDEDKQKI LDKCNEIINW LDKNQTAEKE EFEHQQKELE KVCNPIITKL YQSAGGMPGgMPGGFPGGGA PPSGGASSGP TIEEVD.
Biological Activity:N/A
Usage:Assay Genie’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Uniprot:P11142
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Additional Information

Product type:
Recombinant Protein
Reactivity:
Human
Host Species:
E.Coli
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