Human Heat Shock 70kDa protein 9 Recombinant Protein (CPRT5249)

SKU:
CPRT5249
€278

Description

Data SheetMSDS

HSPA9 Human Recombinant Protein

Name:HSPA9 Human
Synonyms:Mortalin, GRP75, MOT2, GSPA9B, PBP74, MOT-2, MTHSP75, Stress-70 protein mitochondrial, 75 kDa glucose-regulated protein, GRP 75, Heat shock 70 kDa protein 9, Peptide-bindingprotein 74, MOT, HSPA9, HSPA9B, CSA, MGC4500.
Introduction:HSPA9 is part of the heat shock protein 70 family which contains both heat–inducible and constitutively expressed members that are also called heat–shock cognate proteins. HSPA9 encodes a heat–shock cognate protein that is involved in the control of cell proliferation and acts as a chaperone. HSPA9 was restricted to chromosome 5, band q31, a region that is often deleted in myeloid leukemias and myelodysplasia (MDS), makingit a candidate tumor suppressor gene, which is consistent with the biological function of its murine homologue. HSPA9 supresses nuclear translocation, transcriptional activation, and control of centrosome–duplication functions of p53.
Description:Recombinant Human HSPA9 produced in E.Coli is a single,non–glycosylated polypeptide chain containing 654 amino acids (47–679) and having a molecular mass of 71 kDa.HSP9A is expressed with a 20 amino acid His tagfused at N–Terminus and purified by proprietary chromatographic techniques.
Source:Escherichia Coli.
Pack size:50µg
Physical Appearance:Sterile filtered colorless solution.
Formulation:The HSPA9 protein solution contains 20mM Tris–HCl, pH–8, 10% glycerol and 0.5mM DTT.
Solubility:N/A
Stability:Store at 4°C if entire vial will be used within 2–4 weeks. Store, frozen at –20°C for longer periods of time. For longterm storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze–thaw cycles.
Purity:Greater than 95.0% as determined by SDS–PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MASEAIKGAV VGIDLGTTNS CVAVMEGKQA KVLENAEGAR TTPSVVAFTA DGERLVGMPA KRQAVTNPNN TFYATKRLIgRRYDDPEVQK DIKNVPFKIV RASNGDAWVE AHGKLYSPSQ IGAFVLMKMK ETAENYLGHT AKNAVITVPA YFNDSQRQAT KDAGQISGLN VLRVINEPTA AALAYGLDKS EDKVIAVYDL GGGTFDISIL EIQKGVFEVK STNGDTFLGgEDFDQALLRH IVKEFKRETgVDLTKDNMAL QRVREAAEKA KCELSSSVQT DINLPYLTMD SSGPKHLNMK LTRAQFEGIV TDLIRRTIAP CQKAMQDAEV SKSDIGEVIL VGGMTRMPKV QQTVQDLFGR APSKAVNPDE AVAIGAAIQgGVLAGDVTDV LLLDVTPLSL GIETLGGVFT KLINRNTTIP TKKSQVFSTA ADGQTQVEIK VCQGEREMAgDNKLLGQFTL IGIPPAPRGV PQIEVTFDID ANGIVHVSAK DKGTGREQQI VIQSSGGLSK DDIENMVKNA EKYAEEDRRK KERVEAVNMA EGIIHDTETK MEEFKDQLPA DECNKLKEEI SKMRELLARK DSETGENIRQ asSLQQASL KLFEMAYKKM ASEREGSGSS GTGEQKEDQK EEKQ.
Biological Activity:N/A
Usage:Assay Genie’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Uniprot:P38646
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Additional Information

Product type:
Recombinant Protein
Reactivity:
Human
Host Species:
E.Coli
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