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Human IGF-1R Recombinant Protein (hFc Tag) (HDPT0214)

SKU:
HDPT0214
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint
€539
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Description

Human IGF-1R Recombinant Protein (hFc Tag)

Description:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Product name:Human IGF-1R Recombinant Protein (hFc Tag)
Synonyms:IGF1R,IGFR,JTK13,CD221,MGC142170,MGC142172,MGC18216
Type:protein
Size:50 µg
Name:IGF-1R
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:IGF-1R(Glu31-Asn932)+hFc(Glu99-Ala330)
Gene ID:
Uniprot:P08069
Molecular Weight:124.74 kDa