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Human IL17RA Recombinant Protein (His Tag) (HDPT0081)

SKU:
HDPT0081
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint
€656
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Description

Human IL17RA Recombinant Protein (His Tag)

Description:Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product name:Human IL17RA Recombinant Protein (His Tag)
Synonyms:CD217,CDw217,IL-17RA,IL17R,CANDF5,hIL-17R
Type:protein
Size:50 µg
Name:IL17RA
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C- 6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:IL17RA(Leu33-Trp320)+6×His tag
Gene ID:23765
Uniprot:Q96F46
Molecular Weight:34.3 kDa