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Human ROS1 (Proto-oncogene tyrosine-protein kinase ROS)ELISA Kit (HUFI03395)

SKU:
HUFI03395
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P08922
Sensitivity:
18.75pg/ml
Range:
31.25-2000pg/ml
ELISA Type:
Sandwich
Synonyms:
Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Receptor tyrosine kinase c-ros oncogene 1, c-Ros receptor tyrosine kinase, MCF3, ROS, ROS1
Reactivity:
Human
€599
Frequently bought together:

Description

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Human ROS1 (Proto-oncogene tyrosine-protein kinase ROS) ELISA

ROS1 (ROS Proto-Oncogene 1, Receptor Tyrosine Kinase) is a membrane-bound receptor for Growth Factors GDNF (Glial Cell Line Derived Neurotrophic Factor) and NRTN (Neurturin). The ligand binding to the extracellular domain of ROS1 results in the activation of its tyrosine kinase activity. ROS1 has been shown to be upregulated in various human malignancies, such as non-small cell lung cancer, gastric cancer, breast cancer and colorectal cancer. Diseases associated with ROS1 include Lung Cancer Susceptibility 3 and Lung Cancer.