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Human TIM3 Recombinant Protein (mFc-His Tag) (HDPT0030)

SKU:
HDPT0030
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint
€660
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Description

Human TIM3 Recombinant Protein (mFc-His Tag)

Description:The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Product name:Human TIM3 Recombinant Protein (mFc-His Tag)
Synonyms:HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Type:protein
Size:50 µg
Name:TIM3
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:ELISA
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Mouse Fc and 6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:TIM3(Ser22-Gly202)+mFc(Pro99-Lys330)+6×His tag
Gene ID:84868
Uniprot:Q8TDQ0
Molecular Weight:47.5 kDa