Anti-MIA2 Antibody (PACO56026)

Antibody Name:	MIA2 Antibody (PACO56026)
Antibody SKU:	PACO56026
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:	Human
Immunogen:	Recombinant Human Melanoma inhibitory activity protein 2 protein (178-354AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

IHC image of PACO56026 diluted at 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of PACO56026 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Background:

Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity).

Synonyms:

Melanoma inhibitory activity protein 2, MIA2

UniProt Protein Function:	MIA2: May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. Belongs to the MIA/OTOR family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 14q13.2Cellular Component: extracellular regionBiological Process: cholesterol homeostasis
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q96PC5
NCBI GenInfo Identifier:	308153584
NCBI Gene ID:	117153
NCBI Accession:	Q96PC5.3
UniProt Secondary Accession:	Q96PC5,Q9H6C1, A1L4H0
UniProt Related Accession:	Q96PC5
Molecular Weight:	74,089 Da
NCBI Full Name:	Melanoma inhibitory activity protein 2
NCBI Synonym Full Names:	melanoma inhibitory activity 2
NCBI Official Symbol:	MIA2
NCBI Official Synonym Symbols:
NCBI Protein Information:	melanoma inhibitory activity protein 2
UniProt Protein Name:	Melanoma inhibitory activity protein 2
UniProt Synonym Protein Names:
Protein Family:
UniProt Gene Name:	MIA2
UniProt Entry Name:	MIA2_HUMAN

Antibodies	ELISA Kits
MIA2 Antibody (PACO02434)	Human Melanoma inhibitory activity protein 2 (MIA2) ELISA Kit
MIA2 Antibody (PACO07267)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)