Mouse RELM g Recombinant Protein (RPPB0924)
- SKU:
- RPPB0924
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- Q7TM98
- Research Area:
- Cytokines
Description
| Product Name: | Mouse RELM g Recombinant Protein |
| Product Code: | RPPB0924 |
| Size: | 25µg |
| Species: | Mouse |
| Target: | RELM g |
| Synonyms: | Resistin-like gamma, RELMgamma,RELM-?, RELM-g.� |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Lyophilized from a sterile filtered solution containing 0.1 % trifluoroacetic acid (TFA). |
| Solubility: | It is recommended to reconstitute the lyophilized RELM g in sterile 18M?-cm H2O at a concentration of 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized RELM g although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution RELM g Mouse�should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MEGTLESIVE KKVKELLANR DDCPSTVTKT FSCTSITASG RLASCPSGMT VTGCACGYGC GSWDIRDGNT CHCQCSTMDW ATARCCQLA |
| UniProt Code: | Q7TM98 |
RELM-gamma is a novel member of the resistin-like molecule/found in inflammatory zone (RELM/FIZZ) family in mice and rats. Microarray and real-time RT-PCR experiments revealed a repression of RELMgamma mRNA in nasal respiratory epithelium of cigarette smoke-exposed versus untreated rats. The analysis of the physiological tissue-specific expression revealed highest expression in hematopoietic tissues, suggesting a cytokine-like role for RELM-gamma. RELM-gamma-mRNA is detectable in bone marrow, spleen, and lung as well as in peripheral blood granulocytes. Promyelocytic HL60 cells transfected with a RELM-gamma expression plasmid have an increased proliferation rate compared to mock-transfected cells and display an altered response to retinoic acid-induced granulocytic differentiation. Taken together, these data provide the first experimental evidence that RELM-gamma is a secreted molecule with a restricted expression pattern that may play a role in promyelocytic differentiation.
RELM g Mouse Recombinant produced in E.Coli is a non glycosylated, homodimeric polypeptide chain containing 2 x 89 amino acids and having a total molecular mass of 18.9kDa.The RELM is purified by proprietary chromatographic techniques.
