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Anti-MSN Antibody (CAB12463)

SKU:
CAB12463
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-MSN Antibody CAB12463
  • Immunology Antibodies 1 Anti-MSN Antibody CAB12463
  • Immunology Antibodies 1 Anti-MSN Antibody CAB12463
  • Immunology Antibodies 1 Anti-MSN Antibody CAB12463
  • Immunology Antibodies 1 Anti-MSN Antibody CAB12463
€139 - €419
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Description

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Antibody Name:Anti-MSN Antibody
Antibody SKU:CAB12463
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSN (NP_002435.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:Mouse lung, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSN (NP_002435.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPKT ISVR VTTM DAEL EFAI QPNT TGKQ LFDQ VVKT IGLR EVWF FGLQ YQDT KGFS TWLK LNKK VTAQ DVRK ESPL LFKF RAKF YPED VSEE LIQD ITQR LFFL QVKE GILN DDIY CPPE TAVL LASY AVQS KYGD FNKE VHKS GYLA GDKL LPQR VLEQ HKLN KDQW EERI QVWH EEHR GMLR EDAV LEYL KIAQ DLEM YGVN YFSI KNKK GSEL WLGV DALG LNIY EQND RLTP KIGF PWSE IRNI SFND KKFV IKPI DKKA PDFV FYAP RLRI NKRI LALC MGNH ELYM RRRK PDTI
Gene ID:4478
Uniprot:P26038
Cellular Location:Apical cell membrane, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, microvillus membrane
Calculated MW:67kDa
Observed MW:72kDa
Synonyms:MSN, HEL70, IMD50, moesin
Background:Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.
UniProt Protein Function:Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
NCBI Summary:Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
UniProt Code:P26038
NCBI GenInfo Identifier:127234
NCBI Gene ID:4478
NCBI Accession:P26038.3
UniProt Secondary Accession:P26038,P35241, P15311, P26041, P26043, P26040, O35763 P31977,
UniProt Related Accession:P26038
Molecular Weight:67,820 Da
NCBI Full Name:Moesin
NCBI Synonym Full Names:moesin
NCBI Official Symbol:MSN  
NCBI Official Synonym Symbols:HEL70  
NCBI Protein Information:moesin
UniProt Protein Name:Moesin
UniProt Synonym Protein Names:Membrane-organizing extension spike protein
UniProt Gene Name:MSN  
UniProt Entry Name:MOES_HUMAN
Anti-MSN Antibody (CAB12463)Western blot analysis of extracts of various cell lines, using MSN antibody (CAB12463) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Anti-MSN Antibody (CAB12463)Immunohistochemistry of paraffin-embedded human liver cancer using MSN antibody (CAB12463) at dilution of 1:100 (40x lens).
Anti-MSN Antibody (CAB12463)Immunohistochemistry of paraffin-embedded mouse liver using MSN antibody (CAB12463) at dilution of 1:100 (40x lens).
Anti-MSN Antibody (CAB12463)Immunohistochemistry of paraffin-embedded mouse spleen using MSN antibody (CAB12463) at dilution of 1:100 (40x lens).
Anti-MSN Antibody (CAB12463)Immunohistochemistry of paraffin-embedded mouse stomach using MSN antibody (CAB12463) at dilution of 1:100 (40x lens).

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