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Anti-N6-methyladenosine / m6A Antibody (CAB19136)

SKU:
CAB19136
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Mouse
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-N6-methyladenosine / m6A Antibody
Antibody SKU:CAB19136
Antibody Size:20uL, 50uL, 100uL
Application:DB
Reactivity:Human, Mouse, Rat, Other (Wide Range)
Host Species:Mouse
Immunogen:Chemical compounds corresponding to N6-methyladenosine / m6A.
Application:DB
Recommended Dilution:DB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat, Other (Wide Range)
Positive Samples:
Immunogen:Chemical compounds corresponding to N6-methyladenosine / m6A.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:
Uniprot:
Cellular Location:
Calculated MW:
Observed MW:
Anti-N6-methyladenosine / m6A Antibody (CAB19136)`- N6-methyladenosine / m6A Mouse mAb (CAB19136)
Synonyms:N6-methyladenosine, m6A
Background:Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)

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