The PBK Polyclonal Antibody offered by AssayGenie (product code CAB10006) is a valuable tool for researchers studying CD300A and its role in immune regulation. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples. By targeting the CD300A protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in immunology and cancer research.CD300A, also known as an immune inhibitory receptor, plays a crucial role in immune homeostasis by regulating inflammation and allergic reactions.
Its involvement in immune response modulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD300A is essential for developing therapies that can either harness or modulate immune function in these disease contexts.Overall, the PBK Polyclonal Antibody from AssayGenie provides researchers with a reliable tool for investigating the complex role of CD300A in immune regulation and its potential implications for disease research and therapy development.
Product Name:
PBK Polyclonal Antibody
SKU:
CAB21569
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-322 of human PBK (NP_060962.2).
This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55872
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and PBK knockout (KO) 293T cells using PBK Rabbit pAb (CAB21569) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 1s.
