The PRKY Antibody (PACO4774) is a polyclonal antibody designed for research involving the PRKY protein. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry. PRKY is a protein that plays a role in various cellular processes, including signal transduction, transcriptional regulation, and cell proliferation.
It is implicated in cancer progression and has been found to be dysregulated in several types of cancer. By using the PRKY Antibody, researchers can detect and analyze the PRKY protein in different cell types, making it an ideal tool for studies in cancer research and beyond. Understanding the function and regulation of PRKY could provide valuable insights into the development of novel therapeutic approaches for cancer treatment.
Antibody Name:
PRKY Antibody
Antibody SKU:
PACO04774
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human PRKY.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
PRKY; Serine/threonine-protein kinase PRKY
UniProt Protein Function:
PRKY: A chromosomal aberration involving PRKY is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKX. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. cAMP subfamily.Protein type: EC 2.7.11.1; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); AGC group; PKA familyChromosomal Location of Human Ortholog: Yp11.2Molecular Function: ATP binding; protein serine/threonine kinase activityBiological Process: protein amino acid phosphorylation