PRSS8 Antibody, HRP conjugated (PACO55939)
- SKU:
- PACO55939
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
| Antibody Name: | PRSS8 Antibody, HRP conjugated (PACO55939) |
| Antibody SKU: | PACO55939 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Prostasin protein (185-319AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | HRP |
| Background: | Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the γ subunits (SCNN1G). |
| Synonyms: | Prostasin (EC 3.4.21) (Channel-activating protease 1) (CAP1) (Serine protease 8) [Cleaved into: Prostasin light chain; Prostasin heavy chain], PRSS8 |
| UniProt Protein Function: | PRSS8: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:EC 3.4.21.-; Membrane protein, integral; Protease Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: extracellular space; plasma membrane; extracellular region; integral to membrane Molecular Function:protein binding; serine-type peptidase activity; serine-type endopeptidase activity Biological Process: proteolysis |
| NCBI Summary: | This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16651 |
| NCBI GenInfo Identifier: | 2833277 |
| NCBI Gene ID: | 5652 |
| NCBI Accession: | Q16651.1 |
| UniProt Secondary Accession: | Q16651,Q9UCA3, B4DWP2, |
| UniProt Related Accession: | Q16651 |
| Molecular Weight: | 30,519 Da |
| NCBI Full Name: | Prostasin |
| NCBI Synonym Full Names: | protease, serine, 8 |
| NCBI Official Symbol: | PRSS8 |
| NCBI Official Synonym Symbols: | CAP1; PROSTASIN |
| NCBI Protein Information: | prostasin; serine protease 8; channel-activating protease 1 |
| UniProt Protein Name: | Prostasin |
| UniProt Synonym Protein Names: | Channel-activating protease 1; CAP1; Serine protease 8Cleaved into the following 2 chains:Prostasin light chain; Prostasin heavy chain |
| Protein Family: | Prostasin |
| UniProt Gene Name: | PRSS8 |
| UniProt Entry Name: | PRSS8_HUMAN |
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