Recombinant Human ACE2 Protein (His Tag) (RPES0027)
- SKU:
- RPES0027
Description
Background Information
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
| Information | Description |
| Product Name: | Recombinant Human ACE2 Protein (His Tag) |
| Size: | 10µg |
| Product Name: | Recombinant Human ACE2 Protein (His Tag) |
| Activity: | |
| Synonym: | Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2 |
| Protein Construction: | Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a 6His tag at the C-terminus. |
| Sequence: | Gln18-Ser740 |
| Fusion tag: | C-6His |
| Accession: | Q9BYF1 |
| Species: | Human |
| Expressed Host: | Human Cells |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin: | < 1.0 EU per µg as determined by the LAL method. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass: | 84.6 kDa |
| AP Mol Mass: | 103 kDa |
| Formulation: | Supplied as a 0.2 uM filtered solution of 20mM TrisHCl, 150mM NaCl, 0.1mM ZnCl2, 10% Glycerol, pH 7.5. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
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