Recombinant Human Cathepsin B/CTSB Protein (His Tag) SARS-Cov-2 (RPES0033)

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SKU:
RPES0033
£419.39

Description

Background

Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes

Information Description
Product Name:
Recombinant Human Cathepsin B/CTSB Protein (His Tag)
Size:

10µg

SKU:

RPES0033

Activity:
Synonym:
Cathepsin B; APP Secretase; APPS; Cathepsin B1; CTSB; CPSB
Protein Construction:
Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
Sequence:
Arg18-Ile339
Fusion tag:
C-6His
Accession:
P07858
Species:
Human
Expressed Host:
Human Cells
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Endotoxin:
< 1.0 EU per µg as determined by the LAL method.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass:
36.9 kDa
AP Mol Mass:
40 kDa
Formulation:
Supplied as a 0.2 uM filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Reconstitution:
Please refer to the printed manual for detailed information.
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