Recombinant Human Cathepsin B/CTSB Protein (His Tag) SARS-Cov-2 (RPES0033)
- SKU:
- RPES0033
Description
Background
Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
| Information | Description |
| Product Name: | Recombinant Human Cathepsin B/CTSB Protein (His Tag) |
| Size: | 10µg |
| SKU: | RPES0033 |
| Activity: | |
| Synonym: | Cathepsin B; APP Secretase; APPS; Cathepsin B1; CTSB; CPSB |
| Protein Construction: | Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus. |
| Sequence: | Arg18-Ile339 |
| Fusion tag: | C-6His |
| Accession: | P07858 |
| Species: | Human |
| Expressed Host: | Human Cells |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin: | < 1.0 EU per µg as determined by the LAL method. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass: | 36.9 kDa |
| AP Mol Mass: | 40 kDa |
| Formulation: | Supplied as a 0.2 uM filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
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