Klebsiella pneumoniae NEO Recombinant Protein (RPES3535)
- SKU:
- RPES3535
- Product Type:
- Recombinant Protein
- Species:
- Klebsiella pneumoniae
- Research Area:
- Microbiology
Frequently bought together:
Description
system_update_altDatasheet
Klebsiella pneumoniae NEO Recombinant Protein
Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
| Product Name: | Klebsiella pneumoniae NEO Recombinant Protein (RPES3535) |
| Product Code: | RPES3535 |
| Size: | 10µg |
| Species: | Klebsiella pneumoniae |
| Expressed Host: | E.coli |
| Synonyms: | Aminoglycoside 3'-phosphotransferase, APH(3')-II, APH(3')II, Kanamycin kinase type II, Neomycin-kanamycin phosphotransferase type II, neo |
| Accession: | P00552 |
| Sequence: | Met1-Phe264 |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Klebsiella pneumoniae NEO is produced by our E.coli expression system and the target gene encoding Met1-Phe264 is expressed. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 29 kDa |
| AP Mol Mass: | 28-30 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of PBS, pH 7.4, 20% Glycerol. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
