Recombinant Mouse Cathepsin B/CTSB Protein (His Tag) (RPES0034)

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SKU:
RPES0034
€242

Description

Background

Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.

Information Description
Product Name:
Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)
Size:

10µg

SKU:

RPES0034

Activity:
Synonym:
Cathepsin B;Ctsb;Cathepsin B1
Protein Construction:
Recombinant Mouse Cathepsin B is produced by our Mammalian expression system and the target gene encoding His18-Phe339 is expressed with a 6His tag at the C-terminus.
Sequence:
Met 1-Phe 339
Fusion tag:
C-6His
Accession:
P10605
Species:
Mouse
Expressed Host:
Human Cells
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Purity:
> 95 % as determined by SDS-PAGE
Endotoxin:
< 1.0 EU per ?g as determined by the LAL method.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months.
Mol Mass:
36.4 kDa
AP Mol Mass:
32-50kDa
Formulation:
Lyophilized from a 0.2 uM filtered solution of PBS, pH 7.4.
Reconstitution:
Please refer to the printed manual for detailed information.
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