Description
Background
Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.
Information | Description |
Product Name: | Recombinant Mouse Cathepsin L/CTSL Protein His Tag) |
Size: | 10µg |
SKU: | RPES0036 |
Activity: | |
Synonym: | Cathepsin L1; Major excreted protein; p39 cysteine proteinase; Ctsl1;1190035F06Rik |
Protein Construction: | Recombinant Mouse Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Asn334 is expressed with a 6His tag at the C-terminus. |
Sequence: | Thr18-Asn334 |
Fusion tag: | C-6His |
Accession: | P06797 |
Species: | Mouse |
Expressed Host: | Human Cells |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity: | > 95 % as determined by SDS-PAGE |
Endotoxin: | < 1.0 EU per ?g as determined by the LAL method. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months. |
Mol Mass: | 36.8 kDa |
AP Mol Mass: | 13-40kDa |
Formulation: | Lyophilized from a 0.2 uM filtered solution of 20mM PB,150mM NaCl, pH7.4. |
Reconstitution: | Please refer to the printed manual for detailed information. |