Recombinant Mouse Cathepsin L/CTSL Protein His Tag) (RPES0036)

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SKU:
RPES0036
$272

Description

Background

Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.

Information Description
Product Name:
Recombinant Mouse Cathepsin L/CTSL Protein His Tag)
Size:

10µg

SKU:

RPES0036

Activity:
Synonym:
Cathepsin L1; Major excreted protein; p39 cysteine proteinase; Ctsl1;1190035F06Rik
Protein Construction:
Recombinant Mouse Cathepsin L is produced by our Mammalian expression system and the target gene encoding Thr18-Asn334 is expressed with a 6His tag at the C-terminus.
Sequence:
Thr18-Asn334
Fusion tag:
C-6His
Accession:
P06797
Species:
Mouse
Expressed Host:
Human Cells
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Purity:
> 95 % as determined by SDS-PAGE
Endotoxin:
< 1.0 EU per ?g as determined by the LAL method.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months.
Mol Mass:
36.8 kDa
AP Mol Mass:
13-40kDa
Formulation:
Lyophilized from a 0.2 uM filtered solution of 20mM PB,150mM NaCl, pH7.4.
Reconstitution:
Please refer to the printed manual for detailed information.
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