TCA cycle

In TCA (Krebs) cycle, NAD+ is reduced NADH. NADH can then act as a reducing agent to drive energy production in the cell.  

Clearance of ROS

During the clearance of Reactive Oxygen Species (ROS) in the cell, NADPH is oxidized to NADP+. There are many more examples of the interplay between NADPH and NAD+ during cellular metabolism.

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