null
Did you mean: intern alpha 6 cd45 Refine Search
    ​TNF alpha & Inflammation(Post)

    Delving into TNF alpha's critical role in inflammation and its therapeutic targeting. Key Takeaways: TNF alpha is a crucial cytokine in inflammation and apoptosis. Its structure facilita ...

    CD11b: Macrophages and Microglia Marker(Post)

    The immune system plays a critical role in defending the body against pathogens and maintaining tissue homeostasis. Within the intricate network of immune cells, CD11b, also known as inte ...

    Platelet Adhesion Proteins and Ligands: Key Players in Hemostasis and Thrombosis(Post)

    Platelet adhesion is a critical process in the maintenance of hemostasis, the body's response to bleeding. This intricate process involves a series of interactions between platelets, the cellular ...

    Siltuximab: Exploring IL-6 Inhibition in Castleman’s Disease and Research(Post)

    Quick Facts About SiltuximabWhat is Siltuximab?Siltuximab is a monoclonal antibody targeting interleukin-6 (IL-6), a cytokine involved in inflammation and immune regulation.What is the ...

    Natalizumab: Mechanism, Applications, and Emerging Research in Multiple Sclerosis and Crohn's Disease(Post)

    Quick Facts About NatalizumabWhat is Natalizumab?Natalizumab is a monoclonal antibody used to treat multiple sclerosis (MS) and Crohn's disease. It works by blocking immune cells from a ...

    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

    MAPK Signaling in Inflammatory Cytokines Pathways(Post)

    The Mitogen-Activated Protein Kinase (MAPK) pathway is a pivotal signaling cascade that plays a crucial role in mediating cellular responses to various external stimuli. This pathway is intricate ...

    Fibroblast Markers(Post)

    Fibroblasts, essential components of connective tissues, play vital roles in maintaining tissue structure and function. Their remarkable ability to produce and organize the extracellular matrix ...

    Fenofibrate Usage for Diabetes Damage(Post)

    Fenofibrate, also known as FEN, is a drug that is used to lower cholesterol levels. It works by blocking the absorption of dietary cholesterol in the small intestine and therefore, re ...

    Interleukin-8 signalling(Post)

    IL-8 Overview Interleukin-8 (IL-8), also known as CXCL8, was discovered over 30 years ago as a small molecule that could ...

    EGF Family (Post)

    Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced ...

    Biomarkers & Inflammatory markers of atherosclerosis(Post)

    As atherosclerosis is a complex inflammatory disease, there are many influential biomarkers that contribute to the disease’s progression as well as biomarkers from atherosclerosis rel ...

    VEGF: Inflammation and Tumourigenesis(Post)

    What is VEGF? Vascular Endothelial Growth Factors (VEGFs) are a group of homodimeric polypeptides, and are master regulato ...

    Tocilizumab (Actemra®) in COVID-19 Treatment(Post)

    Tocilizumab (Actemra®) in COVID-19 Treatment What is Tocilizumab? Tocilizumab, also called atlizumab, is an immunosuppres ...

    COVID-19 Biomarkers(Post)

    SARS-CoV-2 Background COVID-19 is characterised by a series of biological markers. In some instances, these biomarkers can be used as potent ...

    A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer(Post)

    Mechanical forces are common in biological systems and dominate numerous perturbations that are relevant to human physiology and disease. Mechanobiology is a new field that evaluates the ef ...

    An Overview of the glycoprotein GM-CSF(Post)

    This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in im ...

    CD25 Marker(Post)

    CD25, a key molecule in immune regulation, is integral to the function of activated lymphocytes and regulatory T cells. It's central in mediating immune responses, with implications in autoimmune ...

    Gut Inflammation and Inflammatory Diseases (Post)

    What is Gut Inflammation? The gut, or gastrointestinal (GI) tract is a long tube that starts from the mouth and extends to the anus ...

    Adhesion molecules in atherosclerosis – ICAM1(Post)

    Adhesion Molecules Direct cell-cell interactions are maintained and regulated by cell adhesion molecules. The expression of adhesion molecule ...

    Cytokine Storms: What happens when the immune system overreacts?(Post)

    Discover the critical role of cytokines as signaling molecules in immune responses, their functions, and the impact of their dysregulation, including cytokine storms. Key Takeaways: C ...

    Liposomal nanosilver encapsulation for cytotoxic assays(Post)

    Nanosilver is the most commercialised nanoparticle routinely used for its antibacterial purposes in food preservation, cosmetic and health products such as medical devices and wound treatme ...

    Interleukin 12 (IL-12) in COVID-19 Vaccines(Post)

    Interleukin 12 in COVID-19 Prophylactics Interleukin 12 is a cytokine with wide-reaching effects in the innate and adaptive immune system. O ...

    Cyclophosphamide Side Effects(Post)

    Ovarian cancer is a set of malignancies that start in the ovaries, as well as adjacent portions of the fallopian tubes and peritoneum. Women have two ovaries, one on each side of the ...

    Comprehensive Guide to Mononuclear Cells(Post)

    Mononuclear cells, as the name suggests, refer to a group of white blood cells characterized by th ...

    TNF cytokines and their Receptors(Post)

    The human body is a complex and intricate system where various components work together to maintai ...

    What is an Antigen?(Post)

    Antigen's are foreign molecules recognised by the immune system. Antigens can be protein, carbohydrate, lipid or nucleic acid molecules. Examples include viruses and bacteria as well as f ...

    What are the stages of Parkinson's disease?(Post)

    What is Parkinson’s disease? Parkinson's disease can be seen as a neurodegenerative disease because it is associated with the loss of nerve ce ...

    Macrophage, M1 & M2, Polarization and Function(Post)

    What is a Macrophage? Macrophages are indeed a type of phagocyte, responsible for engulfing and destroying foreign particles and cellular debris. They are larger cells with more cytoplasm a ...

    The Rat Effectively Models Signature Cytokines of T Helper Cells(Post)

    Understanding the immune system's intricacies requires models that accurately reflect its complexity. The rat, as a model organism, plays a crucial role in immunological research, particularly i ...

    Streptococcus pneumoniae: Pathogenesis, Diagnosis, and Treatment(Post)

    Streptococcus pneumoniae, commonly known as pneumococcus, is a Gram-positive, encapsulated bacterium that is a leading cause of respiratory and invasive diseases worldwide. It is part of ...

    Leukemia Inhibitory Factor (LIF)(Post)

    Leukemia Inhibitory Factor (LIF) is a cytokine that plays a crucial role ...

    Decoding Parkinson's Disease: Insights into a Complex Neurological Disorder(Post)

    Parkinson's disease (PD) is a progressive neurological disorder that primarily affects the motor system, leading to a wide array of symptoms ranging from tremors and stiffness to bradykinesia (sl ...

    Neuroimmunology: The Immune System of the CNS(Post)

    What is Neuroimmunology? Neuroimmunology is a multidisciplinary scientific field dedicated to ...

    Adalimumab: Mechanism, Clinical Applications, and the Role of Biosimilars(Post)

    Quick Facts About AdalimumabWhat is Adalimumab?Adalimumab is a fully human monoclonal antibody designed to neutralize tumor necrosis factor-alpha (TNF-α), a key cytokine involved in inf ...

    IL-10 signalling and regulation(Post)

    Explore the complexities of Interleukin-10 (IL-10) signaling and regulation, a crucial aspect in immune response modulation and its dual roles in cancer development and therapy. Key Takeaways ...

    Novel Gene Therapy for Cystic Fibrosis (Post)

    Novel Gene Therapies for Cystic Fibrosis Cystic Fibrosis Cystic fibrosis (CF) is an autosomal recessive, life-limiting disease resulting from gene mutations that encode the cystic fib ...

    Preeclampsia & immune cell regulation | Assay Genie(Post)

    What is preeclampsia? According to the World Health Organization (WHO), one in ten pregnant women is affected by hypertensive disorders, and preeclampsia ...

    Guide to Understanding Th1 and Th2 Cells(Post)

    window.SHOGUN_IMAGE_V2_ELEMENTS = window.SHOGUN_IMAGE_V2_ELEMENTS || new Array(); window.SHOGUN_IMAGE_V2_ELEMENTS.push({ uuid: 's-19118a5d-7dea-4fc9-8267-6237960845ca' }) The T ...

    Physiological and Pathological functions of IL-36(Post)

    By Charlotte O'Donnell PhD Similar to IL-33, IL-36R ligands are involved in maintaining intestinal homeostasis. Analogous to IL-33, d is local ...

    Dendritic Cells - Markers, Activation & Subtypes(Post)

    Exploring the multifaceted role of dendritic cells in immune function and disease. Key Takeaways DCs are professional antigen-presenting cells that capture, process, and pres ...

    Adipokines and Insulin Signaling Pathways: An In-Depth Exploration(Post)

    The prevalence of obesity and its associated metabolic disorders has risen dramatically in recent decades, presenting a significant global health challenge. Adipose tissue, once considered mer ...

    Plonmarlimab: Advancing Anti-GM-CSF Therapy in Inflammatory Diseases(Post)

    Quick Facts About PlonmarlimabWhat is Plonmarlimab?Plonmarlimab is a monoclonal antibody targeting GM-CSF, a cytokine involved in inflammation and immune responses.How does Plonmarlimab ...

    How Furin and ACE2 Interact with the Spike on SARS-CoV-2(Post)

    What is the Coronavirus Spike Protein? COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respirato ...

    Estrogen and Breast Cancer: a Nuclear (Receptor) War(Post)

    By Dr. Lisa Dwane, Postdoctoral Researcher, Royal College of Surgeons in Ireland The first link between estrogen and breast cancer was made in the ...

    Iscalimab: Advancing Research in Autoimmune Diseases and Transplantation(Post)

    What You Need to Know About IscalimabWhat is Iscalimab?Iscalimab (CFZ533) is a monoclonal antibody targeting CD40, a key protein involved in immune system regulation.What is the mechani ...

    CD25 and Tregs: Understanding the Role of Regulatory T Cells in Tumor Immunity(Post)

    Regulatory T cells (Tregs) play a crucial role in maintaining immune balance by suppressing excessive immune responses that could lead to tissue damage. However, in the context of cancer ...

    von Willebrand Factor and Cancer(Post)

    What is von Willebrand Factor? Von Willebrand Factor (VWF) is a crucial glycoprotein that play ...

    Plasma Membrane Markers(Post)

    What is a Plasma Membrane? The plasma membrane, also known as the cell membrane, is a vital component of all cells. It i ...

    TLX as a Novel Therapeutic Target(Post)

    Danka Kozareva PhD Candidate, University College Cork The generation of neurons from stem cells The process of generating ...

    GPCRs (G Protein Coupled Receptors): A Guide(Post)

    What Are GPCRs? GPCRs, or G protein-coupled receptors, are a large family of membrane proteins that play a crucial role in cell sign ...

    Understanding Antibody Staining for Antigen Detection in Flow Cytometry(Post)

    Flow cytometry stands as a pivotal technique in the realms of molecular biology and immunology, enabling the analysis of physical and chemical characteristics of cells or particles as they flow i ...

    B Cell Types, Antigen Recognition & Activation(Post)

    B Cell Types, Antigen Recognition & Activation A comprehensive guide to B cells! Introduction B cells, a vital component of the immune system, ...

    Nod-Like Receptor Signaling Pathway: A Keystone in Innate Immunity(Post)

    The innate immune system, a primary line of defense against pathogens, comprises various cellular and molecular mechanisms. Among these, the Nod-like Receptor (NLR) signaling pathways play a crit ...

    p38 MAPK Signaling Review(Post)

    The p38 MAPK signaling pathway is an intracellular signaling pathway that plays a crucial role in cellular responses to various stressors and inflammatory stimuli. It is a part of the larger MAPK ...

    IL-6 개요(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "IL-6 개요", "author" : { "@type" : "Person", "name" : "Eimear Nolan" }, "datePublished" : ...

    ELISA Sampler Packs(Page)

    ELISA Sampler Packs Based on thousands of citations and years of scientific endeavour, Assay Genie h ...

    Adaptive immune system molecules(Page)

    Co-stimulatory and Co-inhibitory Molecules in Adaptive Immunity The adaptive immune system is in part regulated by a vast array of co-stim ...

    COVID-19 Cytokine Storm Multiplex Assays(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-d7cc806f-05 ...

    Therapeutic Antibody & Biosimilar ELISA Kits(Page)

    document.addEventListener("DOMContentLoaded",(function(){var e=document.querySelector(".page-sidebar");e&&e.remove(),document.querySelectorAll(".page-heading").forEach((function(e){e.re ...

    Rat Multiplex ELISA Panels(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-08000e48-13 ...

    Customer Validated Multiplex Panels(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', ...

    Non-Human Primate Multiplex ELISA Panels(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-2dc821cd-c5c ...

    Adipocytokines(Page)

    Adipocytokines or adipokines are bioactive molecules that are produced by adipose tissue. They comprise cytokines, chemokines coagulation factors and factors involved ...

    ELISpot Assay Kits(Page)

    ELISpot 400x more sensitive than ELISA! Detection & Visualisation at the Single-Cell Leve ...

    Pre-clinical & Large Animal Antibodies(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-90226c4c-be ...

    ELISA Kits(Page)

    Key Interleukin, Chemokine and Cytokine targetsCytokine ELISA KitsFIND OUT MOREMultiplex up to 24 targetsMultiplex AssaysFIND OUT MOREImmuno-oncology and Immuno drug monitoringTherapeut ...

    Mouse Multiplex ELISA Panels(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-6747133c-26 ...

    Citations(Page)

    We're not just any scientific company; our products have made waves in the scientific community. From groundbreaking research to pioneering studies, our reagents and tools are consisten ...

    High Sensitivity Cytokine ELISA Kits & Multiplex Panels(Page)

    High Sensitivity Cytokine ELISA Cytokine ELISA Kits & Multiplex ...

    Animal DIY ELISA Kits(Page)

    Animal DIY ELISA Kits Maximise your research budget! Animal DIY (Do-It-Yourself) ELISA kits a ...

    Immunometabolism Assays(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "Immunometabolism Assays", "author" : { "@type" : "Person", "name" : "Eimear Nolan" }, "da ...

    Beta Actin Monoclonal Antibody(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push( ...

    PharmaGenie ELISA キット(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "PharmaGenie ELISA キット", "author" : { "@type" : "Person", "name" : "Eimear Nolan" }, "dat ...

    QuickStep ELISA Kits(Page)

    QuickStep ELISA Kits 90 Minute 1 Wash Protocol! Explore QuickStep ELISA Kits ...

    PharmaGenie ELISA Kits(Page)

    PharmaGenie ELISA Validated According to ISO Quality Systems ...

    Chemokines(Page)

        Chemokines   Key Research Areas       C Chemokine Ligands XCL1/Lymphot ...

    Transcription Factor Activity Assay Kits(Page)

    Transcription Factor Assays Detect Transcription Factors via indirect ...

    Cell-Based ELISA Kits (Page)

    Cell-Based ELISA Kits No More Western Blots! Over 1,600 ...

    Enzyme Activity Assays(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-015971d6-917 ...

    Phosphorylation ELISA Kits(Page)

    Phosphorylation ELISA Screen cell lysates without Western Blot analysis! Determine phosphorylated protein to verif ...

    SuperSet DIY ELISA Kits(Page)

    SuperSet DIY ELISA Kits Coat your own ELISA Plates! SuperSet DIY ELISA kits allow researchers ...

    ELISA மதிப்பீடு, கொள்கை, நெறிமுறைகள், முறைகள் மற்றும் கருவிகள்(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "ELISA மதிப்பீடு, கொள்கை, நெறிமுறைகள், முறைகள் மற்றும் கருவிகள", "author" : { "@type" : "Person", ...

    Plant & Environmental Stress Assays(Page)

    Plant & Environmental Stress Assays Explore our range of assays to measure reactive oxygen species, pro ...

    Loading Control Antibodies(Page)

    Loading Control Antibodies High Performing Loading Control Antibodies Exp ...

    Metabolism Assays(Page)

    Metabolism Assays At Assay Genie we've developed a range of metabolism assays for researchers to analyse key steps in cellular metabolism.

    TCA Cycle Assays(Page)

    TCA/Krebs Cycle Assays At Assay Genie we've developed a range of TCA assays for researchers to analyse key steps in the Krebs/TCA/Citric Acid cycle pathway. Different Products ...

    TA Cloning(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "TA Cloning", "author" : { "@type" : "Person", "name" : "Eimear Nolan" }, "datePublished" ...

    101 ELISA 문제 해결 팁(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "101 ELISA 문제 해결 팁", "author" : { "@type" : "Person", "name" : "Eimear Nolan" }, " ...

    ELISA 분석법, 원리, 프로토콜, 방법 및 키트(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "ELISA 분석법, 원리, 프로토콜, 방법 및 키트 | Elisa Genie", "author" : { "@type" : "Person", "name" : "Seán M ...

    Human Multiplex ELISA Panels(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-5c77c8b5-9a ...

    Mouse Multiplex Inflammation ELISA Panels(Page)

    The ELISA Genie, Mouse inflammation multiplex assays utilizes multiple bead populations differentiated by size and different levels of fluorescence intensity. With multiple sizes of bea ...

    Multiplex Premixed Panels(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-08a0a ...

    Diabetes & Obesity Assays (Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-38a43fe9-cf0 ...

    Clinical Chemistry Assays(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-d74482a0-ed3 ...

    Human Multiplex Inflammation ELISA Panels(Page)

    The ELISA Genie, Human Inflammation multiplex assays utilizes multiple bead populations differentiated by size and different levels of fluorescence intensity. With multiple sizes of bea ...

    ELISA バッファーとレシピ(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "ELISA バッファーとレシピ", "author" : { "@type" : "Person", "name" : "Seán Mac Fhearraigh PhD." }, ...

    SARS-CoV-2 ELISA Kits(Page)

    window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); window.SHOGUN_IMAGE_ELEMENTS.push({ hoverImage: '', uuid: 's-00706866-14b ...

    एलिसा परीक्षण, सिद्धांत, प्रोटोकॉल, विधियाँ & किट(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "एलिसा परीक्षण, सिद्धांत, प्रोटोकॉल, विधियाँ & किट", "author" : { "@type" : "Person", "name" : ...

    샌드위치 엘리사(Page)

    { "@context" : "http://schema.org", "@type" : "Article", "name" : "샌드위치 엘리사", "author" : { "@type" : "Person", "name" : "Seán Mac Fhearraigh PhD" }, "dateP ...