SLC7A2 Antibody, HRP conjugated (PACO56981)
- SKU:
- PACO56981
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
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Description
| Antibody Name: | SLC7A2 Antibody, HRP conjugated (PACO56981) |
| Antibody SKU: | PACO56981 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Cationic amino acid, transporter 2 protein (604-658AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | HRP |
| Background: | Functions as permease involved in the transport of the cationic amino acid, (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acid, (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acid, (arginine, lysine and ornithine). May play a role in classical or alternative activation of macrophages via its role in arginine transport. |
| Synonyms: | Cationic amino acid, transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid, transporter 2) (Solute carrier family 7 member 2), SLC7A2, ATRC2 CAT2 |
| UniProt Protein Function: | Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport. |
| NCBI Summary: | The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | P52569 |
| NCBI GenInfo Identifier: | 258614005 |
| NCBI Gene ID: | 6542 |
| NCBI Accession: | NP_001008539.3 |
| UniProt Secondary Accession: | P52569,O15291, O15292, Q14CQ6, Q6NSZ7, Q86TC6, B7ZL54 |
| UniProt Related Accession: | P52569 |
| Molecular Weight: | 75,986 Da |
| NCBI Full Name: | cationic amino acid transporter 2 isoform 2 |
| NCBI Synonym Full Names: | solute carrier family 7 member 2 |
| NCBI Official Symbol: | SLC7A2 |
| NCBI Official Synonym Symbols: | CAT2; ATRC2; HCAT2 |
| NCBI Protein Information: | cationic amino acid transporter 2 |
| UniProt Protein Name: | Cationic amino acid transporter 2 |
| UniProt Synonym Protein Names: | Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 |
| Protein Family: | Catalase isozyme |
| UniProt Gene Name: | SLC7A2 |
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