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Anti-TOMM22 Antibody (CAB14548)

SKU:
CAB14548
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

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Antibody Name:Anti-TOMM22 Antibody
Antibody SKU:CAB14548
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human TOMM22 (NP_064628.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:HeLa, HepG2, K-562
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human TOMM22 (NP_064628.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAA VAAA GAGE PQSP DELL PKGD AEKP EEEL EEDD DEEL DETL SERL WGLT EMFP ERVR SAAG ATFD LSLF VAQK MYRF SRA
Gene ID:56993
Uniprot:Q9NS69
Cellular Location:Mitochondrion outer membrane, Single-pass membrane protein
Calculated MW:15kDa
Observed MW:16kDa
Synonyms:TOMM22, 1C9-2, MST065, MSTP065, TOM22
Background:The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.
UniProt Protein Function:TOMM22: Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. Belongs to the Tom22 family.
UniProt Protein Details:

Protein type:Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: mitochondrion; membrane; mitochondrial outer membrane translocase complex; mitochondrial inner membrane; integral to membrane

Molecular Function:protein binding; protein transmembrane transporter activity

Biological Process: cellular protein metabolic process; protein targeting to mitochondrion; protein import into mitochondrial outer membrane

NCBI Summary:The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NS69
NCBI GenInfo Identifier:24212074
NCBI Gene ID:56993
NCBI Accession:Q9NS69.3
UniProt Secondary Accession:Q9NS69,Q9CPQ3,
UniProt Related Accession:Q9NS69
Molecular Weight:142
NCBI Full Name:Mitochondrial import receptor subunit TOM22 homolog
NCBI Synonym Full Names:translocase of outer mitochondrial membrane 22 homolog (yeast)
NCBI Official Symbol:TOMM22  
NCBI Official Synonym Symbols:1C9-2; TOM22; MST065; MSTP065  
NCBI Protein Information:mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; translocase of outer membrane 22 kDa subunit homolog
UniProt Protein Name:Mitochondrial import receptor subunit TOM22 homolog
UniProt Synonym Protein Names:1C9-2; Translocase of outer membrane 22 kDa subunit homolog
Protein Family:Mitochondrial import receptor
UniProt Gene Name:TOMM22  
UniProt Entry Name:TOM22_HUMAN
Anti-TOMM22 Antibody (CAB14548)Western blot analysis of extracts of various cell lines, using TOMM22 antibody (CAB14548) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.

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