ZNF420 Antibody (PACO20964)
- SKU:
- PACO20964
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | ZNF420 Antibody (PACO20964) |
| Antibody SKU: | PACO20964 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human ZNF420 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20964(ZNF420 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20964(ZNF420 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | May be involved in transcriptional regulation. |
| Synonyms: | zinc finger protein 420 |
| UniProt Protein Function: | ZNF420: May be involved in transcriptional regulation.Protein type: Transcription factor; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.12Cellular Component: nucleusMolecular Function: protein binding; DNA binding; metal ion binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016] |
| UniProt Code: | Q8TAQ5 |
| NCBI GenInfo Identifier: | 22095393 |
| NCBI Gene ID: | 147923 |
| NCBI Accession: | NP_653290 |
| UniProt Secondary Accession: | Q8TAQ5 |
| UniProt Related Accession: | Q8TAQ5 |
| Molecular Weight: | 80kDa |
| NCBI Full Name: | zinc finger protein 420 isoform b |
| NCBI Synonym Full Names: | zinc finger protein 420 |
| NCBI Official Symbol: | ZNF420Â Â |
| NCBI Official Synonym Symbols: | APAKÂ Â |
| NCBI Protein Information: | zinc finger protein 420 |
| UniProt Protein Name: | Zinc finger protein 420 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF420Â Â |
| UniProt Entry Name: | ZN420_HUMAN |
| Antibodies |
| ZNF420 Antibody (PACO02509) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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