4-1BB/CD137 Monoclonal Antibody (CAB22167)
- SKU:
- CAB22167
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | 4-1BB/CD137 Monoclonal Antibody |
SKU: | CAB22167 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-186 of human 4-1BB/CD137 (NP_001552.2). |
Sequence: | LQDP CSNC PAGT FCDN NRNQ ICSP CPPN SFSS AGGQ RTCD ICRQ CKGV FRTR KECS STSN AECD CTPG FHCL GAGC SMCE QDCK QGQE LTKK GCKD CCFG TFND QKRG ICRP WTNC SLDG KSVL VNGT KERD VVCG PSPA DLSP GASS VTPP APAR EPGH SPQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:20000 |
Synonyms: | ILA; 4-1BB; CD137; CDw137; IMD109; 4-1BB/CD137 |
Positive Sample: | 293T transfected with 4-1BB/CD137 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 28kDa |
Observed MW: | 24-28kDa 40-50kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Purification Method: | Affinity purification |
Gene ID: | 3604 |
Clone Number: | ARC55368 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |