null

ABCD1 Rabbit Polyclonal Antibody (CAB12141)

SKU:
CAB12141
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
  • Signal Transduction Antibodies 1 Anti-ABCD1 Antibody CAB12141
  • Signal Transduction Antibodies 1 Anti-ABCD1 Antibody CAB12141
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ABCD1 Rabbit Polyclonal Antibody
SKU:CAB12141
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 340-500 of human ABCD1 (NP_000024.2).
Sequence:SASG LLMV AVPI ITAT GYSE SDAE AVKK AALE KKEE ELVS ERTE AFTI ARNL LTAA ADAI ERIM SSYK EVTE LAGY TARV HEMF QVFE DVQR CHFK RPRE LEDA QAGS GTIG RSGV RVEG PLKI RGQV VDVE QGII CENI PIVT PSGE VVVA SLNI RVEE G
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:ALD; AMN; ALDP; ABC42; ABCD1
Positive Sample:LO2,U-87MG,HeLa
Conjugate:Unconjugated
Cellular Localization:Multi-pass membrane protein, Peroxisome membrane.
Calculated MW:83kDa
Observed MW:83kDa

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Purification Method:Affinity purification
Gene ID:215
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ABCD1 Rabbit pAb (CAB12141) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

Related Products