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ABI2 Rabbit Polyclonal Antibody (CAB14992)

SKU:
CAB14992
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ABI2 Rabbit Polyclonal Antibody
SKU:CAB14992
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABI2 (NP_001269854.1).
Sequence:HKEK VARR EIGI LTTN KNTS RTHK IIAP ANLE RPVR YIRK PIDY TILD DIGH GVKW LLRF KVST QNMK MGGL PRTT PPTQ KPPS PPMS GKGT LGRH SPYR T
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:AIP1; ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB; ABI2
Positive Sample:U-251MG,Mouse brain
Conjugate:Unconjugated
Cellular Localization:Cell projection, Cytoplasm, cytoskeleton, filopodium, lamellipodium.
Calculated MW:56kDa
Observed MW:50kDa

Enables several functions, including SH3 domain binding activity; identical protein binding activity; and ubiquitin protein ligase binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction; positive regulation of cellular component organization; and zonula adherens assembly. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in several cellular components, including filopodium tip; lamellipodium; and nucleoplasm. Part of SCAR complex. Is active in adherens junction. Colocalizes with actin filament.

Purification Method:Affinity purification
Gene ID:10152
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ABI2 Rabbit pAb (CAB14992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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