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Anti-ACAA2 Antibody (CAB15778)

SKU:
CAB15778
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • Metabolism Antibodies 3 Anti-ACAA2 Antibody CAB15778
  • Metabolism Antibodies 3 Anti-ACAA2 Antibody CAB15778
  • Metabolism Antibodies 3 Anti-ACAA2 Antibody CAB15778
  • Metabolism Antibodies 3 Anti-ACAA2 Antibody CAB15778
  • Metabolism Antibodies 3 Anti-ACAA2 Antibody CAB15778
€139 - €419
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Description

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Antibody Name:Anti-ACAA2 Antibody
Antibody SKU:CAB15778
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ACAA2 (NP_006102.2).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, A-549, HeLa, Mouse heart, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ACAA2 (NP_006102.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MALL RGVF VVAA KRTP FGAY GGLL KDFT ATDL SEFA AKAA LSAG KVSP ETVD SVIM GNVL QSSS DAIY LARH VGLR VGIP KETP ALTI NRLC GSGF QSIV NGCQ EICV KEAE VVLC GGTE SMSQ APYC VRNV RFGT KLGS DIKL EDSL WVSL TDQH VQLP MAMT AENL AVKH KISR EECD KYAL QSQQ RWKA ANDA GYFN DEMA PIEV KTKK GKQT MQVD EHAR PQTT LEQL QKLP PVFK KDGT VTAG NA
Gene ID:10449
Uniprot:P42765
Cellular Location:Mitochondrion
Calculated MW:41kDa
Observed MW:50kDa
Synonyms:ACAA2, DSAEC
Background:The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.
UniProt Protein Function:ACAA2: Abolishes BNIP3-mediated apoptosis and mitochondrial damage. Belongs to the thiolase family.
UniProt Protein Details:

Protein type:Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.1.16; Lipid Metabolism - fatty acid; Lipid Metabolism - fatty acid elongation in mitochondria; Transferase

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function:acetyl-CoA C-acyltransferase activity; protein binding; RNA binding

Biological Process: fatty acid beta-oxidation

NCBI Summary:The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]
UniProt Code:P42765
NCBI GenInfo Identifier:167614485
NCBI Gene ID:10449
NCBI Accession:NP_006102.2
UniProt Secondary Accession:P42765,Q9BUT6,
UniProt Related Accession:P42765
Molecular Weight:
NCBI Full Name:3-ketoacyl-CoA thiolase, mitochondrial
NCBI Synonym Full Names:acetyl-CoA acyltransferase 2
NCBI Official Symbol:ACAA2  
NCBI Official Synonym Symbols:DSAEC  
NCBI Protein Information:3-ketoacyl-CoA thiolase, mitochondrial
UniProt Protein Name:3-ketoacyl-CoA thiolase, mitochondrial
UniProt Synonym Protein Names:Acetyl-CoA acyltransferase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1
Protein Family:3-ketoacyl-CoA thiolase
UniProt Gene Name:ACAA2  
Anti-ACAA2 Antibody (CAB15778)Western blot analysis of extracts of various cell lines, using ACAA2 antibody (CAB15778) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Anti-ACAA2 Antibody (CAB15778)Immunohistochemistry of paraffin-embedded Human colon carcinoma using ACAA2 Rabbit pAb (CAB15778) at dilution of 1:100 (40x lens).
Anti-ACAA2 Antibody (CAB15778)Immunofluorescence analysis of C6 cells using ACAA2 antibody (CAB15778) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-ACAA2 Antibody (CAB15778)Immunofluorescence analysis of L929 cells using ACAA2 antibody (CAB15778) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-ACAA2 Antibody (CAB15778)Immunofluorescence analysis of U-2 OS cells using ACAA2 antibody (CAB15778) at dilution of 1:100. Blue: DAPI for nuclear staining.

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