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Acetyl-Histone H2B (K15) Antibody (PACO02980)

SKU:
PACO02980
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Acetyl-Histone H2B (K15) Antibody
Antibody SKU:PACO02980
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse
Immunogen:synthesized peptide derived from human Histone H2B around the acetylation site of K15.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s
UniProt Protein Function:H2BFS: a core component of the nucleoosome. The nucleosome, a basic organizational unit of chromosomal DNA, is octrameric, consisting of two molecules each of histones H2B, H2A, H3, H4. The octamer wraps approximately 147 bp of DNA. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 21q22.3Cellular Component: cytoplasm; extracellular space; nucleoplasm; nucleusMolecular Function: DNA binding; protein heterodimerization activityBiological Process: antibacterial humoral response; defense response to Gram-positive bacterium; innate immune response in mucosa; nucleosome assembly; substantia nigra development
UniProt Protein Details:
NCBI Summary:
UniProt Code:P57053
NCBI GenInfo Identifier:9973351
NCBI Gene ID:102724334
NCBI Accession:P57053.2
UniProt Secondary Accession:P57053,Q5R2W0, A0AVF9
UniProt Related Accession:P57053
Molecular Weight:13,944 Da
NCBI Full Name:Histone H2B type F-S
NCBI Synonym Full Names:
NCBI Official Symbol:LOC102724334  
NCBI Official Synonym Symbols:
NCBI Protein Information:histone H2B type F-S-like
UniProt Protein Name:Histone H2B type F-S
UniProt Synonym Protein Names:Histone H2B.s; H2B/s
Protein Family:Histone
UniProt Gene Name:H2BFS  
UniProt Entry Name:H2BFS_HUMAN

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