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Anti-AMD1 Antibody (CAB8537)

SKU:
CAB8537
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
AMD1
ADOMETDC
AMD
SAMDC
€139 - €419
Frequently bought together:

Description

Product Name:AMD1 Rabbit pAb
Product Code:CAB8537
Size:20uL, 50uL, 100uL
Synonyms:AMD1, ADOMETDC, AMD, SAMDC
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, Mouse skeletal muscle, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RRFI LKTC GTTL LLKA LVPL LKLA RDYS GFDS IQSF FYSR KNFM KPSH QGYP HRNF QEEI EFLN AIFP NGAA YCMG RMNS DCWY LYTL DFPE SRVI SQPD QTLE ILMS ELDP AVMD QFYM KDGV TAKD VTRE SGIR DLIP GSVI DATM FNPC GYSM NGMK SDGT YWTI HITP EPEF SYVS FETN LSQT SYDD LIRK VVEV FKPG KFVT TLFV NQSS KCRT VLAS PQKI EGFK RLDC QSAM FNDY NFVF TSFA KKQQ QQQS
Gene ID:262
Uniprot:P17707
Calculated MW:21kDa/38kDa
Observed MW:32KDa/42KDa
UniProt Protein Function:AMD1: an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.[provided by RefSeq, Jul 2010]
UniProt Protein Details:

Protein type:Amino Acid Metabolism - arginine and proline; Lyase; Amino Acid Metabolism - cysteine and methionine; EC 4.1.1.50

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: cytosol

Molecular Function:adenosylmethionine decarboxylase activity

Biological Process: S-adenosylmethioninamine biosynthetic process; spermidine biosynthetic process; spermine biosynthetic process; polyamine metabolic process

NCBI Summary:This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013]
UniProt Code:P17707
NCBI GenInfo Identifier:116241324
NCBI Gene ID:262
NCBI Accession:P17707.2
UniProt Secondary Accession:P17707,Q5VXN4, Q5VXN6, Q9BWK4, E1P5F7,
UniProt Related Accession:P17707
Molecular Weight:21,301 Da
NCBI Full Name:S-adenosylmethionine decarboxylase proenzyme
NCBI Synonym Full Names:adenosylmethionine decarboxylase 1
NCBI Official Symbol:AMD1  
NCBI Official Synonym Symbols:AMD; SAMDC; ADOMETDC  
NCBI Protein Information:S-adenosylmethionine decarboxylase proenzyme; S-adenosylmethionine decarboxylase 1
UniProt Protein Name:S-adenosylmethionine decarboxylase proenzyme
Protein Family:S-adenosylmethionine decarboxylase proenzyme
UniProt Gene Name:AMD1  
UniProt Entry Name:DCAM_HUMAN

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