AMH Rabbit Polyclonal Antibody (CAB8538)
- SKU:
- CAB8538
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Description
Product Name: | AMH Rabbit Polyclonal Antibody |
SKU: | CAB8538 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-560 of human AMH (NP_000470.3). |
Sequence: | PAPL HDPT SAPW ATAL ARRV AAEL QAAA AELR SLPG LPPA TAPL LARL LALC PGGP GGLG DPLR ALLL LKAL QGLR VEWR GRDP RGPG RAQR SAGA TAAD GPCA LREL SVDL RAER SVLI PETY QANN CQGV CGWP QSDR NPRY GNHV VLLL KMQV RGAA LARP PCCV PTAY AGKL LISL SEER ISAH HVPN MVAT ECGC R |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | MIF; MIS; AMH |
Positive Sample: | SKOV3,Mouse testis,Rat liver,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 59kDa |
Observed MW: | 60kDa |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.
Purification Method: | Affinity purification |
Gene ID: | 268 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |