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AMH Rabbit Polyclonal Antibody (CAB8538)

SKU:
CAB8538
Product Type:
Antibody
Applications:
WB
IHC
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Developmental Biology
€139 - €419
Frequently bought together:

Description

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Product Name:AMH Rabbit Polyclonal Antibody
SKU:CAB8538
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 360-560 of human AMH (NP_000470.3).
Sequence:PAPL HDPT SAPW ATAL ARRV AAEL QAAA AELR SLPG LPPA TAPL LARL LALC PGGP GGLG DPLR ALLL LKAL QGLR VEWR GRDP RGPG RAQR SAGA TAAD GPCA LREL SVDL RAER SVLI PETY QANN CQGV CGWP QSDR NPRY GNHV VLLL KMQV RGAA LARP PCCV PTAY AGKL LISL SEER ISAH HVPN MVAT ECGC R
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100
Synonyms:MIF; MIS; AMH
Positive Sample:SKOV3,Mouse testis,Rat liver,Rat testis
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:59kDa
Observed MW:60kDa

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.

Purification Method:Affinity purification
Gene ID:268
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using AMH Rabbit pAb (CAB8538) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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