null

Anti-CHD1L Antibody (CAB17558)

SKU:
CAB17558
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ALC1
CHDL
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

Product Name:CHD1L Rabbit mAb
Product Code:CAB17558
Size:20uL, 50uL, 100uL
Synonyms:ALC1, CHDL
Applications:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human CHD1L
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HepG2
Immunogen:A synthesized peptide derived from human CHD1L
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9557
Uniprot:Q86WJ1
Calculated MW:101kDa
Observed MW:101KDa
UniProt Protein Function:CHD1L: DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. Belongs to the SNF2/RAD54 helicase family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.6.4.12; Helicase; DNA-binding

Chromosomal Location of Human Ortholog: 1q12

Cellular Component: cytoplasm; nucleoplasm; nucleus; plasma membrane

Molecular Function:ATP-dependent DNA helicase activity; ATPase activity; nucleotide binding; protein binding

Biological Process: chromatin remodeling; DNA repair; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, preincision complex stabilization; response to DNA damage stimulus

NCBI Summary:This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012]
UniProt Code:Q86WJ1
NCBI GenInfo Identifier:311033359
NCBI Gene ID:9557
NCBI Accession:Q86WJ1.2
UniProt Secondary Accession:Q86WJ1,Q53EZ3, Q5VXX7, Q6DD94, Q6PK83, Q86XH3, Q96HF7 Q96SP3, Q9BVJ1, A5YM64, B4DDE1, B5MDZ7,
UniProt Related Accession:Q86WJ1
Molecular Weight:69,139 Da
NCBI Full Name:Chromodomain-helicase-DNA-binding protein 1-like
NCBI Synonym Full Names:chromodomain helicase DNA binding protein 1 like
NCBI Official Symbol:CHD1L  
NCBI Official Synonym Symbols:ALC1; CHDL  
NCBI Protein Information:chromodomain-helicase-DNA-binding protein 1-like
UniProt Protein Name:Chromodomain-helicase-DNA-binding protein 1-like
UniProt Synonym Protein Names:Amplified in liver cancer protein 1
Protein Family:Chromodomain-helicase-DNA-binding protein
UniProt Gene Name:CHD1L  
UniProt Entry Name:CHD1L_HUMAN

Related Products