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Anti-Human IgG3 Antibody (CAB19713)

SKU:
CAB19713
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IgG3
€139 - €419
Frequently bought together:

Description

Product Name:Human IgG3 Rabbit mAb
Product Code:CAB19713
Size:20uL, 50uL, 100uL
Synonyms:IgG3
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Human IgG3
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:human plasma
Immunogen:A synthesized peptide derived from human Human IgG3
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3502
Uniprot:P01860
Calculated MW:kDa
Observed MW:60KDa
UniProt Protein Function:Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
UniProt Code:P01860
NCBI GenInfo Identifier:193806361
NCBI Gene ID:3502
NCBI Accession:P01860.2
UniProt Secondary Accession:P01860,A0A075B6N8, A2NU35,
UniProt Related Accession:P01860
Molecular Weight:41,287 Da
NCBI Full Name:Immunoglobulin heavy constant gamma 3
NCBI Synonym Full Names:immunoglobulin heavy constant gamma 3 (G3m marker)
NCBI Official Symbol:IGHG3  
NCBI Official Synonym Symbols:IgG3  
UniProt Protein Name:Immunoglobulin heavy constant gamma 3
UniProt Synonym Protein Names:HDC; Heavy chain disease protein; Ig gamma-3 chain C regionCurated
UniProt Gene Name:IGHG3  

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