The Anti-PDZK1 Antibody (CAB8874) is a high-quality reagent designed for the detection and analysis of PDZK1, a protein involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PDZK1 protein, researchers can accurately study its expression and function in different cell types, making it a valuable tool for studies in cell biology and molecular research.PDZK1 is a scaffolding protein that plays a crucial role in maintaining cellular functions and regulating signaling pathways.
Its diverse functions in cell organization and signaling make it a target of interest in research related to cancer, cardiovascular diseases, and metabolic disorders. Investigating the role of PDZK1 in these contexts can provide valuable insights into disease mechanisms and potential therapeutic strategies aimed at targeting PDZK1 for treatment.Overall, the Anti-PDZK1 Antibody (CAB8874) offers researchers a reliable tool for exploring the functions and mechanisms of PDZK1, contributing to a better understanding of its role in cellular processes and disease development.
Product Name:
PDZK1 Rabbit Monoclonal Antibody
SKU:
CAB8874
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 420-519 of human PDZK1 (Q5T2W1).
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
5174
Clone Number:
ARC1334
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunofluorescence analysis of paraffin-embedded rat kidney using PDZK1 Rabbit mAb (CAB8874) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
