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Anti-TIGIT Antibody (CAB20350)

SKU:
CAB20350
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
VSIG9
VSTM3
WUCAM
€139 - €419
Frequently bought together:

Description

Product Name:TIGIT Rabbit pAb
Product Code:CAB20350
Size:50uL, 100uL
Synonyms:VSIG9, VSTM3, WUCAM
Applications:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human TIGIT.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Human plasma, Mouse lung
Immunogen:Recombinant protein of human TIGIT.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:201633
Uniprot:Q495A1
Calculated MW:26kDa
Observed MW:30kDa
UniProt Protein Function:Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
UniProt Code:Q495A1
NCBI GenInfo Identifier:121943253
NCBI Gene ID:201633
NCBI Accession:Q495A1.1
UniProt Secondary Accession:Q495A1,Q495A3, Q5JPD8, Q6MZS2, Q8N877
UniProt Related Accession:Q495A1
Molecular Weight:18,432 Da
NCBI Full Name:T-cell immunoreceptor with Ig and ITIM domains
NCBI Synonym Full Names:T cell immunoreceptor with Ig and ITIM domains
NCBI Official Symbol:TIGIT  
NCBI Official Synonym Symbols:VSIG9; VSTM3; WUCAM  
NCBI Protein Information:T-cell immunoreceptor with Ig and ITIM domains
UniProt Protein Name:T-cell immunoreceptor with Ig and ITIM domains
UniProt Synonym Protein Names:V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3
Protein Family:T-cell immunoreceptor with Ig and ITIM domains
UniProt Gene Name:TIGIT  
UniProt Entry Name:

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