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ATG7 Rabbit Polyclonal Antibody (CAB0691)

SKU:
CAB0691
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy
  • Autophagy Antibodies Anti-ATG7 Antibody CAB0691
  • Autophagy Antibodies Anti-ATG7 Antibody CAB0691
  • Autophagy Antibodies Anti-ATG7 Antibody CAB0691
  • Autophagy Antibodies Anti-ATG7 Antibody CAB0691
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ATG7 Rabbit Polyclonal Antibody
SKU:CAB0691
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 500-676 of human ATG7 (NP_006386.1).
Sequence:LGFD TFVV MRHG LKKP KQQG AGDL CPNH PVAS ADLL GSSL FANI PGYK LGCY FCND VVAP GDST RDRT LDQQ CTVS RPGL AVIA GALA VELM VSVL QHPE GGYA IASS SDDR MNEP PTSL GLVP HQIR GFLS RFDN VLPV SLAF DKCT ACSS KVLD QYER EGFN FLAK VFNS SHSF L
Tested Applications:IHC-P IF/ICC ELISA
Recommended Dilution:IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:GSA7; APG7L; SCAR31; APG7-LIKE; ATG7
Positive Sample:Jurkat,Rat testis
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Preautophagosomal structure.
Calculated MW:78kDa
Observed MW:78kDa

This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:10533
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageImmunohistochemistry analysis of paraffin-embedded human colon carcinoma using ATG7 Rabbit pAb (CAB0691) at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

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