Bovine ATF Recombinant Protein (RPPB2893)
- SKU:
- RPPB2893
- Product type:
- Recombinant Protein
- Size:
- 150mg
- Species:
- Bovine
- Target:
- ATF
- Synonyms:
- Serotransferrin
- Transferrin
- Siderophilin
- Beta-1-metal-binding globulin
- Uniprot:
- Q29443
Description
| Product Name: | Bovine ATF Recombinant Protein |
| Product Code: | RPPB2893 |
| Size: | 150mg |
| Species: | Bovine |
| Target: | ATF |
| Synonyms: | Serotransferrin, Transferrin, Siderophilin, Beta-1-metal-binding globulin, TF, PRO1557, PRO2086, DKFZp781D0156, Apo Transferrin, ATF. |
| Physical Appearance: | Sterile Filtered off-white lyophilized (freeze-dried) powder. |
| Formulation: | The protein (1mg/ml) was lyophilized with no additives. |
| Solubility: | It is recommended to reconstitute the lyophilized Apo Transferrin in sterile 18M?-cm H2O not less than 1gr/30ml in 20min. at 20-25C.� |
| Stability: | Lyophilized Bovine Apo Transferrin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Bovine Apo Transferrin should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
Transferrin is the iron-transport protein of vertebrate serum and donates iron to cells through interaction with a specific membrane receptor, CD71. Transferrin appears to be indispensable for most cells growing in tissue culture. It is referred to frequently as a growth factor because, in analogy to other growth factor-receptor interactions, proliferating cells express high numbers of transferrin receptors, and the binding of transferrin to their receptors is needed for cells to initiate and maintain their DNA synthesis. Apart from its role as an iron transport protein transferrin acts as a cytokine and has functions that may not be related to its iron-carrying capacity.Bovine Transferrin is a crucial component for the cultivation of mammalian cells in- vitro. Bovine Transferrin is Critical for long-term cells growth in-vitro. Bovine Transferrin is used as detoxificant in media by binding contaminating metal ions. Bovine Transferrin is often used as a nutrient in fermentation media for recombinant protein and biopharmaceutical production. Additional common uses of Bovine Transferrin are Molecular weight, Affinity purification of anti-human transferrin antibodies and also as receptor mediated transfection of molecules such as DNA, into cells.
Bovine Apo Transferrin is a glycoprotein of approximately 77kDa.
| UniProt Protein Function: | Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q29443 |
| NCBI GenInfo Identifier: | 114326282 |
| NCBI Gene ID: | 280705 |
| NCBI Accession: | NP_803450.2 |
| UniProt Secondary Accession: | Q29443,Q0IIK2 |
| UniProt Related Accession: | Q29443 |
| Molecular Weight: | 77,753 Da |
| NCBI Full Name: | serotransferrin |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | TF�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | serotransferrin |
| UniProt Protein Name: | Serotransferrin |
| UniProt Synonym Protein Names: | Beta-1 metal-binding globulin; Siderophilin |
| Protein Family: | Serotransferrin |
| UniProt Gene Name: | TF�� |
| UniProt Entry Name: | TRFE_BOVIN |
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