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CD63 Rabbit Monoclonal Antibody (CAB19023)

SKU:
CAB19023
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CD63 Rabbit Monoclonal Antibody
SKU:CAB19023
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 103-203 of human CD63 (NP_001771.1).
Sequence:AGYV FRDK VMSE FNNN FRQQ MENY PKNN HTAS ILDR MQAD FKCC GAAN YTDW EKIP SMSK NRVP DSCC INVT VGCG INFN EKAI HKEG CVEK IGGW LRKN V
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:2000 - 1:10000
Synonyms:MLA1; ME491; LAMP-3; OMA81H; TSPAN30; CD63
Positive Sample:A375,RAW 264.7,Mouse kidney
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Endosome, Late endosome membrane, Lysosome membrane, Melanosome, Multi-pass membrane protein, multivesicular body.
Calculated MW:17kDa/23kDa/25kDa
Observed MW:30-65kDa

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Purification Method:Affinity purification
Gene ID:967
Clone Number:ARC51703
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from A375 cells, using CD63 Rabbit mAb (CAB19023) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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